Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 6/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | THPO | P40225 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11047112 | 0.98 | P4HTM (0.56) | P4HTMKDM4EKMT2AHIF1ATDP1 | |
| SCHEMBL19556485 | 0.94 | P4HTM (0.61) | P4HTMKDM4EKMT2AHIF1ATDP1 | |
| SCHEMBL11061928 | 0.88 | KDM4E (0.60) | P4HTMKDM4EKMT2AHIF1ATDP1 | |
| SCHEMBL11059897 | 0.83 | KDM4E (0.56) | P4HTMKDM4EKMT2AHIF1ATDP1 | |
| SCHEMBL11045319 | 0.83 | KDM4E (0.56) | P4HTMKDM4EKMT2AHIF1ATDP1 | |
| SCHEMBL11061422 | 0.78 | P4HTM (0.59) | P4HTMKDM4EKMT2AHIF1ATDP1 | |
| SCHEMBL4870118 | 0.76 | LNPEP (0.46) | KDM4EKMT2AALDH1A1MEN1MAPT | |
| SCHEMBL12420688 | 0.75 | NFE2L2 (0.52) | P4HTMKDM4EKMT2AHIF1ATDP1 | |
| SCHEMBL28108319 | 0.75 | P4HTM (0.71) | P4HTMKDM4EKMT2AHIF1ATDP1 | |
| SCHEMBL19555927 | 0.74 | KDM4E (0.40) | P4HTMKDM4EKMT2AHIF1ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1984004302-A1 | SUBSTITUTED PICOLINIC ACIDS, PROCESSES FOR THEIR PREPARATION, THEIR USE AND MEDICAMENTS CONTAINING THEM | BYK GULDEN LOMBERG CHEM FAB (DE) | 1984-11-08 | — | — | WO | disclosed |