Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | NQO1 | P15559 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.40 |
| ▸ | HBB | P68871 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13990807 | 0.83 | KDM4E (0.56) | KDM4ENQO1MAPTHSD17B10ESR2 | |
| SCHEMBL7674855 | 0.80 | KDM4E (0.53) | KDM4ENQO1MAPTHSD17B10ESR2 | |
| SCHEMBL5252024 | 0.80 | NQO1 (0.52) | KDM4ENQO1MAPTHSD17B10ESR2 | |
| SCHEMBL4618673 | 0.77 | KDM4E (0.53) | KDM4ENQO1MAPTHSD17B10ESR2 | |
| SCHEMBL6784748 | 0.77 | KDM4E (0.53) | KDM4ENQO1MAPTHSD17B10ESR2 | |
| SCHEMBL910695 | 0.77 | L3MBTL1 (0.59) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL16770699 | 0.77 | KDM4E (0.49) | KDM4ENQO1MAPTHSD17B10ESR2 | |
| SCHEMBL1682636 | 0.76 | KDM4E (0.49) | KDM4ENQO1MAPTHSD17B10ESR2 | |
| SCHEMBL7273575 | 0.75 | KDM4E (0.51) | KDM4ENQO1MAPTHSD17B10ESR2 | |
| SCHEMBL910978 | 0.75 | APLNR (0.58) | MAPTHSD17B10MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4487772-A | CARDIOTONIC AGENTS | OTSUKA PHARMACEUTICAL CO. LTD. (JP) | 1984-12-11 | — | — | US | disclosed |
| US-4468402-A | Carbostyril derivatives, process for producing the same and cardiotonic compositions containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-08-28 | — | — | US | disclosed |
| US-4454130-A | CARDIOTONIC, HYPOTENSIVE AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-06-12 | — | — | US | disclosed |