Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 6/20 | 0.51 |
| ▸ | ATP4B | P51164 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11048062 | 0.79 | ATP4A (0.51) | ATP4AATP4BMEN1CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL11050041 | 0.78 | ATP4A (0.50) | ATP4AATP4BMEN1CYP1A2CYP3A4 | |
| SCHEMBL14328786 | 0.75 | ATP4A (0.67) | ATP4AATP4BMEN1CYP1A2CYP3A4 | |
| SCHEMBL11048807 | 0.75 | CHEK1 (0.55) | ATP4AATP4BMEN1CYP1A2CYP3A4 | |
| SCHEMBL2191435 | 0.73 | ATP4A (0.77) | ATP4AATP4BMEN1CYP1A2CYP3A4 | |
| SCHEMBL2189812 | 0.71 | ATP4A (0.86) | ATP4AATP4BMEN1CYP1A2CYP3A4 | |
| SCHEMBL11069625 | 0.70 | ATP4A (0.70) | ATP4AATP4BMEN1CYP1A2CYP3A4 | |
| SCHEMBL2192718 | 0.69 | ATP4A (0.79) | ATP4AATP4BMEN1CYP1A2CYP3A4 | |
| SCHEMBL5633386 | 0.69 | ATP4A (0.60) | ATP4AATP4BMEN1CYP1A2CYP3A4 | |
| SCHEMBL2191115 | 0.68 | ATP4A (1.00) | ATP4AATP4BMEN1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4468400-A | PEPTIC ULCERS | SCHERING CORPORATION (US) | 1984-08-28 | — | — | US | disclosed |