Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.55 |
| ▸ | AURKA | O14965 | 1/20 | 0.55 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.55 |
| ▸ | JAK2 | O60674 | 1/20 | 0.55 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.55 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.55 |
| ▸ | PAK4 | O96013 | 1/20 | 0.55 |
| ▸ | ABL1 | P00519 | 1/20 | 0.55 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.55 |
| ▸ | LCK | P06239 | 1/20 | 0.55 |
| ▸ | FYN | P06241 | 1/20 | 0.55 |
| ▸ | CSF1R | P07333 | 1/20 | 0.55 |
| ▸ | RET | P07949 | 1/20 | 0.55 |
| ▸ | IGF1R | P08069 | 1/20 | 0.55 |
| ▸ | MET | P08581 | 1/20 | 0.55 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.55 |
| ▸ | PIM1 | P11309 | 1/20 | 0.55 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.55 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.55 |
| ▸ | PRKACA | P17612 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9283403 | 0.75 | CHEK1 (0.60) | CHEK1AURKADAPK3JAK2PRKD3 | |
| SCHEMBL11048062 | 0.75 | ATP4A (0.51) | CHEK1AURKADAPK3JAK2PRKD3 | |
| SCHEMBL11048065 | 0.75 | ATP4A (0.51) | CHEK1AURKADAPK3JAK2PRKD3 | |
| Hydrochloric Acid SCHEMBL11050041 | 0.74 | ATP4A (0.50) | CHEK1AURKADAPK3JAK2PRKD3 | |
| SCHEMBL5633386 | 0.72 | ATP4A (0.60) | ATP4AATP4BMEN1CYP1A2CYP3A4 | |
| SCHEMBL197301 | 0.71 | CHEK1 (1.00) | CHEK1AURKADAPK3JAK2PRKD3 | |
| SCHEMBL10690155 | 0.69 | ATP4A (0.55) | ATP4AATP4BMEN1CYP1A2CYP3A4 | |
| SCHEMBL5633236 | 0.67 | ATP4A (0.60) | ATP4AATP4BMEN1CYP1A2CYP3A4 | |
| SCHEMBL10694506 | 0.65 | ATP4A (0.48) | ATP4AATP4BMEN1CYP1A2CYP3A4 | |
| SCHEMBL10686121 | 0.65 | ATP4A (0.46) | ATP4AATP4BMEN1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4468400-A | PEPTIC ULCERS | SCHERING CORPORATION (US) | 1984-08-28 | — | — | US | disclosed |