Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 6/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.33 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.33 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.33 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11058588 | 0.87 | APEX1 (0.48) | APEX1ENPP2POLBCASP6CTDSP1 | |
| SCHEMBL11067366 | 0.86 | APEX1 (0.48) | APEX1ENPP2KDM4EMAPTHDAC1 | |
| SCHEMBL11050005 | 0.85 | APEX1 (0.53) | APEX1ENPP2CASP6CTDSP1MAPT | |
| SCHEMBL9145883 | 0.85 | APEX1 (0.64) | APEX1ENPP2POLBCASP6CTDSP1 | |
| SCHEMBL11063383 | 0.84 | TIMP3 (0.43) | APEX1ENPP2POLBCASP6CTDSP1 | |
| SCHEMBL11044460 | 0.83 | APEX1 (0.53) | APEX1ENPP2POLBCASP6CTDSP1 | |
| SCHEMBL11057878 | 0.83 | APEX1 (0.55) | APEX1ENPP2POLBCASP6CTDSP1 | |
| SCHEMBL11087743 | 0.83 | APEX1 (0.51) | APEX1ENPP2CASP6CTDSP1ALDH1A1 | |
| SCHEMBL11084677 | 0.83 | APEX1 (0.51) | APEX1ENPP2POLBCASP6CTDSP1 | |
| SCHEMBL11060526 | 0.83 | APEX1 (0.51) | APEX1ENPP2POLBCASP6CTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4473498-A | Water-soluble, fiber-reactive organic dyestuffs containing a β-chloro-ethylsulfonyl-methyl-benzoic acid amide group | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-09-25 | — | — | US | disclosed |