Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TIMP3 | P35625 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11065797 | 0.90 | TIMP3 (0.44) | APEX1ENPP2ATMALDH1A1LMNA | |
| SCHEMBL11048509 | 0.87 | APEX1 (0.63) | APEX1ENPP2ALDH1A1LMNAKMT2A | |
| SCHEMBL11048438 | 0.86 | APEX1 (0.47) | APEX1ENPP2ALDH1A1MAPTKDM4E | |
| SCHEMBL11049551 | 0.84 | ENPP2 (0.39) | APEX1ENPP2ATMALDH1A1KMT2A | |
| SCHEMBL11052845 | 0.82 | APEX1 (0.46) | APEX1ENPP2ALDH1A1KMT2AMAPT | |
| SCHEMBL11063383 | 0.81 | TIMP3 (0.43) | APEX1ENPP2ALDH1A1KMT2AMAPT | |
| SCHEMBL11052975 | 0.79 | CASP6 (0.47) | ENPP2ALDH1A1LMNANT5ESMN1; SMN2 | |
| SCHEMBL11050005 | 0.78 | APEX1 (0.53) | APEX1ENPP2ALDH1A1KMT2AMAPT | |
| SCHEMBL11049881 | 0.77 | APEX1 (0.57) | APEX1ENPP2ALDH1A1LMNAKMT2A | |
| SCHEMBL9145883 | 0.77 | APEX1 (0.64) | APEX1ENPP2ALDH1A1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4473498-A | Water-soluble, fiber-reactive organic dyestuffs containing a β-chloro-ethylsulfonyl-methyl-benzoic acid amide group | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-09-25 | — | — | US | disclosed |