SCHEMBL11048587

SCHEMBL11048587

Cc1c(F)c(C#N)c(F)c(F)c1C#N

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TRPV4 Q9HBA0 1/20 0.32
ALDH1A1 P00352 1/20 0.31
ATM Q13315 1/20 0.30
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19021858 0.94 TRPV4 (0.35) TRPV4ALDH1A1ATMKDM4E
SCHEMBL7068601 0.92 TRPV4 (0.31) TRPV4ALDH1A1
SCHEMBL18162324 0.92 TRPV4 (0.33) TRPV4ALDH1A1ATMKDM4E
SCHEMBL25613867 0.89 TRPV4 (0.32) TRPV4ALDH1A1ATMKDM4E
SCHEMBL13989354 0.89 TRPV4 (0.32) TRPV4ALDH1A1ATMKDM4E
SCHEMBL19021860 0.89 TRPV4 (0.32) TRPV4ALDH1A1ATMKDM4E
SCHEMBL18159203 0.88 TRPV4 (0.35) TRPV4ALDH1A1ATMKDM4E
SCHEMBL16627106 0.86 TRPV4 (0.31) TRPV4ALDH1A1
SCHEMBL25613889 0.86 TRPV4 (0.31) TRPV4ALDH1A1
SCHEMBL406500 0.86 TRPV4 (0.31) TRPV4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230242562-A1 Compound of Formula (I), a Semiconductor Material Comprising at Least One Compound of Formula (I), a Semiconductor Layer Comprising at Least One Compound of Formula (I) and an Electronic Device Comprising at Least One Compound of Formula (I) NOVALED GMBH (DE) 2023-08-03 US disclosed
EP-3789451-B1 POROUS CYCLODEXTRIN POLYMERIC MATERIALS UNIV CORNELL (US) 2023-06-07 EP disclosed
US-20220388991-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2022-12-08 US disclosed
US-20180093252-A1 POROUS CYCLODEXTRIN POLYMERIC MATERIALS AND METHODS OF MAKING AND USING SAME NATIONAL SCIENCE FOUNDATION 2018-04-05 US disclosed
US-9855545-B2 Porous cyclodextrin polymeric materials and methods of making and using same CORNELL UNIVERSITY (US) 2018-01-02 US disclosed
US-20170173560-A1 POROUS CYCLODEXTRIN POLYMERIC MATERIALS AND METHODS OF MAKING AND USING SAME NATIONAL SCIENCE FOUNDATION 2017-06-22 US disclosed
US-9624314-B2 Porous cyclodextrin polymeric materials and methods of making and using same CORNELL UNIVERSITY (US) 2017-04-18 US disclosed
US-20160304630-A1 POROUS CYCLODEXTRIN POLYMERIC MATERIALS AND METHODS OF MAKING AND USING SAME CORNELL UNIVERSITY 2016-10-20 US disclosed
US-9371429-B2 Ladder polymers with intrinsic microporosity and process for production thereof NATIONAL RESEARCH COUNCIL OF CANADA 2016-06-21 US disclosed
US-20140243441-A1 LADDER POLYMERS WITH INTRINSIC MICROPOROSITY AND PROCESS FOR PRODUCTION THEREOF NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2014-08-28 US disclosed
US-8067026-B2 Drug release regions for medical devices, which include polycyclic-structure-containing polymers BOSTON SCIENTIFIC SCIMED, INC. (US) 2011-11-29 US disclosed
US-20110190409-A1 LADDER POLYMERS WITH INSTRINSIC MICROPOROSITY AND PROCESS FOR PRODUCTION THEREOF NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2011-08-04 US disclosed
US-20070209505-A1 High Flux Mixed Matrix Membranes for Separations UOP LLC 2007-09-13 US disclosed
EP-0119701-A1 Grignard syntheses IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-09-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230242562-A1 Compound of Formula (I), a Semiconductor Material Comprising at Least One Compound of Formula (I), a Semiconductor Layer Comprising at Least One Compound of Formula (I) and an Electronic Device Comprising at Least One Compound of Formula (I) AFF4, AFF1, AFF2 TRPV4 573/4885ALDH1A1 722/4885ATM 2587/4885
US-20110190409-A1 LADDER POLYMERS WITH INSTRINSIC MICROPOROSITY AND PROCESS FOR PRODUCTION THEREOF CCR3, CNOT9, AR TRPV4 2577/4885ALDH1A1 1922/4885ATM 917/4885
US-20220388991-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE LSM12, TCF12, OR10J3 TRPV4 926/4885ALDH1A1 973/4885ATM 2691/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.