SCHEMBL7068601

SCHEMBL7068601

Cc1c(F)c(F)c(C#N)c(F)c1C#N

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TRPV4 Q9HBA0 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13989354 0.92 TRPV4 (0.32) TRPV4ALDH1A1
SCHEMBL11048587 0.92 TRPV4 (0.32) TRPV4ALDH1A1
SCHEMBL16627106 0.90 TRPV4 (0.31) TRPV4ALDH1A1
SCHEMBL1808331 0.89 TRPV4 (0.33) TRPV4ALDH1A1
SCHEMBL25613941 0.89 ALDH1A1 (0.37) TRPV4ALDH1A1
SCHEMBL25613867 0.86 TRPV4 (0.32) TRPV4ALDH1A1
SCHEMBL18159203 0.86 TRPV4 (0.35) TRPV4ALDH1A1
SCHEMBL19021858 0.86 TRPV4 (0.35) TRPV4ALDH1A1
SCHEMBL406500 0.84 TRPV4 (0.31) TRPV4ALDH1A1
SCHEMBL25613889 0.84 TRPV4 (0.31) TRPV4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6362365-B1 DEFLUORINATION OF THE TETRAFUOROISOPHALATE DERIVATIVE USING ORGANO ALKYL METALLIC COMPOUND TO ALKYLATE AT THE 6 POSITION AND THEN DECARBOXYLATION CLARIANT GMBH (DE) 2002-03-26 US claimed
EP-1002786-A1 Process for the preparation of trifluorobenzoic acids Clariant GmbH (DE) 2000-05-24 EP claimed
US-20230242562-A1 Compound of Formula (I), a Semiconductor Material Comprising at Least One Compound of Formula (I), a Semiconductor Layer Comprising at Least One Compound of Formula (I) and an Electronic Device Comprising at Least One Compound of Formula (I) NOVALED GMBH (DE) 2023-08-03 US disclosed
EP-1002786-B1 Process for the preparation of trifluorobenzoic acids CLARIANT GMBH (DE) 2003-06-18 EP disclosed
US-6362365-B1 DEFLUORINATION OF THE TETRAFUOROISOPHALATE DERIVATIVE USING ORGANO ALKYL METALLIC COMPOUND TO ALKYLATE AT THE 6 POSITION AND THEN DECARBOXYLATION CLARIANT GMBH (DE) 2002-03-26 US disclosed
EP-1002786-A1 Process for the preparation of trifluorobenzoic acids Clariant GmbH (DE) 2000-05-24 EP disclosed
EP-1002786-A1 Process for the preparation of trifluorobenzoic acids Clariant GmbH (DE) 2000-05-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230242562-A1 Compound of Formula (I), a Semiconductor Material Comprising at Least One Compound of Formula (I), a Semiconductor Layer Comprising at Least One Compound of Formula (I) and an Electronic Device Comprising at Least One Compound of Formula (I) AFF4, AFF1, AFF2 TRPV4 573/4885ALDH1A1 722/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.