Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10830521 | 0.88 | SLC6A3 (0.49) | SLC6A3SLC22A1SIGMAR1OPRK1OPRM1 | |
| SCHEMBL10830485 | 0.84 | SLC6A3 (0.46) | SLC6A3SLC22A1ALDH1A1SIGMAR1MAPT | |
| SCHEMBL11046164 | 0.83 | SLC6A3 (0.66) | SLC6A3SLC22A1SIGMAR1OPRK1OPRM1 | |
| SCHEMBL10830570 | 0.83 | OPRM1 (0.49) | SLC6A3TSHROPRM1 | |
| SCHEMBL141801 | 0.82 | SLC6A3 (0.50) | SLC6A3SIGMAR1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL10830557 | 0.81 | SLC6A3 (0.50) | SLC6A3SIGMAR1OPRM1 | |
| Hydrochloric Acid SCHEMBL10969030 | 0.80 | SLC6A3 (0.49) | SLC6A3SIGMAR1OPRM1 | |
| SCHEMBL10831088 | 0.80 | SLC6A3 (0.49) | SLC6A3SLC22A1CPB2SIGMAR1OPRK1 | |
| SCHEMBL11047922 | 0.78 | SLC6A3 (0.52) | SLC6A3SLC22A1CPB2SIGMAR1OPRM1 | |
| SCHEMBL10830185 | 0.77 | SLC6A3 (0.51) | SLC6A3SLC22A1ALDH1A1SIGMAR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4478836-A | 1-Aryl 2-aminomethyl cyclopropane carboxyamide (Z) derivatives and their use as useful drugs in the treatment of disturbances of the central nervous system | PIERRE FABRE S.A. (FR) | 1984-10-23 | — | — | US | disclosed |