Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11048502 | 0.90 | ABCB11 (0.35) | MDM2TSHRALDH1A1SMN1; SMN2HTT | |
| SCHEMBL11047283 | 0.90 | BACE1 (0.32) | MDM2MEN1KMT2AHTT | |
| SCHEMBL11045314 | 0.83 | MDM2 (0.33) | MDM2MEN1TSHRKMT2AALDH1A1 | |
| SCHEMBL11006876 | 0.80 | MDM2 (0.39) | MDM2MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL11057525 | 0.76 | PTGS2 (0.37) | MDM2MEN1TSHRKMT2AALDH1A1 | |
| SCHEMBL9792244 | 0.76 | MDM2 (0.35) | MDM2MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL11048683 | 0.74 | ABCB11 (0.36) | TSHRKMT2AALDH1A1SMN1; SMN2HTT | |
| SCHEMBL11064390 | 0.73 | PTGS2 (0.37) | MDM2MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL11045936 | 0.73 | BACE1 (0.34) | MEN1KMT2A | |
| SCHEMBL8812100 | 0.73 | RECQL (0.50) | MEN1TSHRKMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4456759-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIPYRETICS, ANTICOAGULANTS, AND MUSCLE RELAXANTS | SYNTEX (U.S.A.) INC. (US) | 1984-06-26 | — | — | US | disclosed |
| US-4347185-A | DECARBOXYLATION OF THE 1,1-DICARBOXYLATES | SYNTEX (U.S.A.) INC. (US) | 1982-08-31 | — | — | US | disclosed |