Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11044891 | 0.76 | KMT2A (0.54) | KMT2AMEN1TSHRMAPK1HIF1A | |
| SCHEMBL11258472 | 0.75 | MEN1 (0.46) | KMT2AMEN1TSHRMAPK1HIF1A | |
| SCHEMBL12238642 | 0.69 | KMT2A (0.60) | KMT2AMEN1TSHRMAPK1HIF1A | |
| SCHEMBL11242169 | 0.68 | MEN1 (0.39) | KMT2AMEN1TSHRMAPK1HIF1A | |
| SCHEMBL9488032 | 0.67 | CYP19A1 (0.47) | CYP3A4CYP17A1CYP19A1CYP3A5 | |
| SCHEMBL11242414 | 0.67 | CYP19A1 (0.59) | KMT2AMEN1TSHRMAPK1HIF1A | |
| SCHEMBL10764412 | 0.66 | MEN1 (0.62) | KMT2AMEN1TSHRMAPK1HIF1A | |
| SCHEMBL11258403 | 0.65 | CYP19A1 (0.50) | KMT2AMEN1TSHRMAPK1HIF1A | |
| SCHEMBL11261677 | 0.65 | TSHR (0.43) | KMT2AMEN1TSHRMAPK1HIF1A | |
| SCHEMBL11248026 | 0.65 | CYP19A1 (0.47) | KMT2AMEN1TSHRMAPK1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4469902-A | FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1984-09-04 | — | — | US | claimed |