Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | RORC | P51449 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11256138 | 0.88 | CYP19A1 (0.40) | CYP19A1RORCMEN1KMT2ANPSR1 | |
| SCHEMBL11258472 | 0.86 | MEN1 (0.46) | CYP19A1MAPK1TSHRMEN1KMT2A | |
| SCHEMBL11250364 | 0.84 | CYP19A1 (0.47) | CYP19A1MAPK1TSHRMEN1KMT2A | |
| SCHEMBL11249211 | 0.83 | CYP19A1 (0.40) | CYP19A1MAPK1TSHRRORCMEN1 | |
| SCHEMBL11242169 | 0.78 | MEN1 (0.39) | CYP19A1MAPK1TSHRMEN1KMT2A | |
| SCHEMBL11261677 | 0.77 | TSHR (0.43) | CYP19A1MAPK1TSHRMEN1KMT2A | |
| SCHEMBL11242414 | 0.77 | CYP19A1 (0.59) | CYP19A1MAPK1TSHRMEN1KMT2A | |
| SCHEMBL11048505 | 0.74 | ALDH1A1 (0.47) | TSHRMEN1KMT2ACHRM2CHRM3 | |
| SCHEMBL11248026 | 0.74 | CYP19A1 (0.47) | CYP19A1MAPK1TSHRMEN1KMT2A | |
| SCHEMBL11286839 | 0.73 | CYP19A1 (0.37) | CYP19A1MEN1KMT2ANPSR1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322442-A | INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1982-03-30 | — | — | US | disclosed |