Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GSR | P00390 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5376291 | 1.00 | TSHR (0.33) | TSHRMEN1KMT2AGSRCA5A | |
| SCHEMBL251470 | 1.00 | — | — | |
| SCHEMBL264006 | 0.86 | — | — | |
| SCHEMBL264764 | 0.86 | — | — | |
| SCHEMBL27701175 | 0.86 | GSR (0.31) | TSHRGSR | |
| SCHEMBL15688967 | 0.85 | — | — | |
| SCHEMBL11837270 | 0.85 | — | — | |
| SCHEMBL254925 | 0.85 | MEN1 (0.33) | MEN1KMT2AALDH1A1 | |
| SCHEMBL9242242 | 0.85 | GSR (0.36) | TSHRGSRCA5ACA5B | |
| SCHEMBL14327294 | 0.85 | TSHR (0.32) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4486603-A | Preparation of trans cyclohexane 1,4-diamine | AKZONA INCORPORATED (US) | 1984-12-04 | — | — | US | disclosed |
| US-4467114-A | Preparation of trans cyclohexane 1,4-diurea | AKZONA INCORPORATED (US) | 1984-08-21 | — | — | US | disclosed |
| US-4457871-A | Preparation of trans cyclohexane,1,4-diisocyanate and related compounds | AKZONA INCORPORATED (US) | 1984-07-03 | — | — | US | disclosed |
| US-4439370-A | Preparation of trans cyclohexane 1,4-diisocyanate | AKZONA INCORPORATED (US) | 1984-03-27 | — | — | US | disclosed |
| US-4418211-A | Preparation of trans-cyclohexane-1,4-disulphonyl urea | AKZONA INCORPORATED (US) | 1983-11-29 | — | — | US | disclosed |
| US-4275223-A | Preparation of trans-cyclohexane-1,4-diurethanes | AKZONA INCORPORATED (US) | 1981-06-23 | — | — | US | disclosed |
| US-4203916-A | Preparation of trans cyclohexane 1,4 diisocyanate | AKZONA INCORPORATED (US) | 1980-05-20 | — | — | US | disclosed |