SCHEMBL254925

SCHEMBL254925

CC1CCC([N+](=O)[O-])CC1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
MAPT P10636 2/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14327293 1.00 MEN1 (0.33) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL11845772 0.91
SCHEMBL251470 0.85
SCHEMBL5376291 0.85 TSHR (0.33) MEN1KMT2AALDH1A1
SCHEMBL11049355 0.85 TSHR (0.33) MEN1KMT2AALDH1A1
SCHEMBL16174020 0.84
SCHEMBL16173997 0.74
SCHEMBL264006 0.73
SCHEMBL27701175 0.73 GSR (0.31)
SCHEMBL264764 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9676763-B2 Method of treating Ebola PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2017-06-13 US disclosed
US-20160024066-A1 Small Molecule Inhibitors of Ebola and Lassa Fever Viruses and Methods of Use THE BRIGHAM AND WOMEN'S HOSPITAL, INC. 2016-01-28 US disclosed
US-9193705-B2 Small molecule inhibitors of ebola and lassa fever viruses and methods of use PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2015-11-24 US disclosed
US-8563219-B2 Resist composition and method for producing resist pattern SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-10-22 US disclosed
US-8530137-B2 Photoresist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-09-10 US disclosed
US-8530137-B2 Photoresist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-09-10 US disclosed
US-20130231332-A1 SMALL MOLECULE INHIBITORS OF EBOLA AND LASSA FEVER VIRUSES AND METHODS OF USE NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2013-09-05 US disclosed
US-8329377-B2 Imide compound and chemically amplified resist composition containing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-12-11 US disclosed
US-8329377-B2 Imide compound and chemically amplified resist composition containing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-12-11 US disclosed
US-20120219909-A1 RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-08-30 US disclosed
US-20100028807-A1 Imide Compound and Chemically Amplified Resist Composition Containing The Same SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2010-02-04 US disclosed
US-20100028807-A1 Imide Compound and Chemically Amplified Resist Composition Containing The Same SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2010-02-04 US disclosed
EP-1430019-B1 SPHINGOLIPIDS YISSUM RES DEV CO (IL) 2009-12-30 EP disclosed
US-20080190855-A1 removing toxic heavy metal ions from water for drinking water filtration or environmental cleanup; carbon attached directly to the amino acid via carboxyl groups on the surface; converting surface carboxyl groups to acyl halide groups and then contacting with amino acid; carbon electrode; graphite powder ISIS INNOVATION LIMITED (GB) 2008-08-14 US disclosed
EP-0341496-B1 Modified diene polymer rubbers SUMITOMO CHEMICAL CO (JP) 1993-10-20 EP disclosed
US-5219938-A Reacting a living polymer of a conjugated diene with a tin or silicon compound and with a nitro compound, a phosphoryl chloride, aminosilane, an acrylamide or an aminovinylsilane; auto tires; impact strength; cold resistance; storage SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-06-15 US disclosed
US-5128416-A Automobile tire treads SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-07-07 US disclosed
US-4957976-A IMPROVED PROPERTIES FOR AUTOMOBILE TIRES, MODIFIED WITH PHOSPHORYL CHLORIDE SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1990-09-18 US disclosed
EP-0341496-A2 Modified diene polymer rubbers SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-11-15 EP disclosed
US-3971825-A (5,6) (10,11) BIS-METHYLENE, BRONCHODILATORS SANKYO COMPANY LIMITED (JA) 1976-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080190855-A1 removing toxic heavy metal ions from water for drinking water filtration or environmental cleanup; carbon attached directly to the amino acid via carboxyl groups on the surface; converting surface carboxyl groups to acyl halide groups and then contacting with amino acid; carbon electrode; graphite powder GLUL, SLC3A2, ARGLU1 MEN1 4371/4885KMT2A 930/4885MAPT 3604/4885
US-20160024066-A1 Small Molecule Inhibitors of Ebola and Lassa Fever Viruses and Methods of Use LASP1, LAS1L, HSP90B1 MEN1 3233/4885KMT2A 4278/4885MAPT 1825/4885
US-20130231332-A1 SMALL MOLECULE INHIBITORS OF EBOLA AND LASSA FEVER VIRUSES AND METHODS OF USE LASP1, LAS1L, HSP90B1 MEN1 3233/4885KMT2A 4278/4885MAPT 1825/4885
US-20100028807-A1 Imide Compound and Chemically Amplified Resist Composition Containing The Same IGF1R, CCNA1, MYC MEN1 98/4885KMT2A 219/4885MAPT 3812/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.