⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11049355 | 1.00 | TSHR (0.33) | — | |
| SCHEMBL5376291 | 1.00 | TSHR (0.33) | — | |
| SCHEMBL264006 | 0.86 | — | — | |
| SCHEMBL264764 | 0.86 | — | — | |
| SCHEMBL27701175 | 0.86 | GSR (0.31) | — | |
| SCHEMBL15688967 | 0.85 | — | — | |
| SCHEMBL11837270 | 0.85 | — | — | |
| SCHEMBL254925 | 0.85 | MEN1 (0.33) | — | |
| SCHEMBL9242242 | 0.85 | GSR (0.36) | — | |
| SCHEMBL14327294 | 0.85 | TSHR (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 356 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117623936-A | Novel method for synthesizing cyclopropylamine | 中昊(大连)化工研究设计院有限公司 | 2024-03-01 | — | — | CN | claimed |
| CN-117430513-A | New method for synthesizing cyclopropylamine | 中昊(大连)化工研究设计院有限公司 | 2024-01-23 | — | — | CN | claimed |
| CN-116621710-B | Synthesis method of cyclopropylamine | 山东国邦药业有限公司 | 2023-10-27 | — | — | CN | claimed |
| CN-116621710-A | Synthesis method of cyclopropylamine | 山东国邦药业有限公司 | 2023-08-22 | — | — | CN | claimed |
| CN-107459476-B | Anti-indoline cyclopropylamine compound and preparation method, pharmaceutical composition and application thereof | 中国科学院上海药物研究所 | 2022-06-24 | — | — | CN | claimed |
| CN-107935859-A | A kind of synthetic method of nitro cyclopropane | 西安近代化学研究所 | 2018-04-20 | — | — | CN | claimed |
| US-20140323727-A1 | NOVEL PROCESS FOR PREPARING PHENYLCYCLOPROPYLAMINE DERIVATIVES USING NOVEL INTERMEDIATES | ACTAVIS GROUP PTC EHF (IS) | 2014-10-30 | — | — | US | claimed |
| US-8680290-B2 | Isoxazoline derivatives and their use as herbicides | SYNGENTA LIMITED (GB) | 2014-03-25 | — | — | US | claimed |
| US-20130150577-A1 | NOVEL PROCESS FOR PREPARING PHENYLCYCLOPROPYLAMINE DERIVATIVES USING NOVEL INTERMEDIATES | ACTAVIS GROUP PTC EHF (IS) | 2013-06-13 | — | — | US | claimed |
| EP-2589587-A1 | Synthesis of nitrogen substituted cyclopropanes | Chemo Ibérica, S.A. (ES) | 2013-05-08 | — | — | EP | claimed |
| EP-2560939-A2 | NOVEL PROCESS FOR PREPARING PHENYLCYCLOPROPYLAMINE DERIVATIVES USING NOVEL INTERMEDIATES | Actavis Group Ptc Ehf (IS) | 2013-02-27 | — | — | EP | claimed |
| WO-2011132083-A2 | NOVEL PROCESS FOR PREPARING PHENYLCYCLOPROPYLAMINE DERIVATIVES USING NOVEL INTERMEDIATES | ACTAVIS GROUP PTC EHF (IS) | 2011-10-27 | — | — | WO | claimed |
| CN-101052628-B | Isoxazoline derivatives and herbicidal use thereof | SYNGENTA LTD | 2011-07-27 | — | — | CN | claimed |
| EP-1789401-B1 | ISOXAZOLINE DERIVATIVES AND THEIR USE AS HERBICIDES | SYNGENTA LTD (GB) | 2010-03-03 | — | — | EP | claimed |
| CN-120081748-A | Preparation method of cyclopropylamine | 内蒙古源宏精细化工有限公司 | 2025-06-03 | — | — | CN | disclosed |
| CN-119569576-A | Synthesis method of cyclopropylamine compound | 西安近代化学研究所 | 2025-03-07 | — | — | CN | disclosed |
| CN-119569534-A | Synthesis method of cyclopropyl alcohol | 西安近代化学研究所 | 2025-03-07 | — | — | CN | disclosed |
| US-3903179-A | Method for preparing nitrocyclopropane from 3-chloro-1-nitropropane | CHEVRON RESEARCH COMPANY, SAN FRANCISCO, CA. A CORP. OF DE. | 1975-09-02 | — | — | US | disclosed |
| US-3903179-A | Method for preparing nitrocyclopropane from 3-chloro-1-nitropropane | CHEVRON RESEARCH COMPANY, SAN FRANCISCO, CA. A CORP. OF DE. | 1975-09-02 | — | — | US | disclosed |
| US-3903180-A | Making nitrocyclopropane from 3-chloro-1-nitropropane | CHEVRON RESEARCH COMPANY, SAN FRANCISCO, CA. A CORP. OF DE. | 1975-09-02 | — | — | US | disclosed |