Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GCK | P35557 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4535436 | 0.79 | ALDH1A1 (0.46) | NPC1RAB9AKMT2ASMN1; SMN2GLA | |
| SCHEMBL8830201 | 0.79 | NPC1 (0.39) | NPC1RAB9AGCKKMT2ASMN1; SMN2 | |
| SCHEMBL3367184 | 0.71 | F2 (0.41) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL10919877 | 0.70 | TSHR (0.40) | NPC1RAB9AGCKKMT2ASMN1; SMN2 | |
| SCHEMBL10919613 | 0.69 | GCK (0.48) | NPC1RAB9AGCKKMT2AMEN1 | |
| SCHEMBL6122699 | 0.69 | NPC1 (0.42) | NPC1RAB9AGCKKMT2ASMN1; SMN2 | |
| SCHEMBL9267486 | 0.69 | NPC1 (0.42) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL11058656 | 0.69 | HDAC1 (0.44) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL10550826 | 0.69 | MLYCD (0.44) | KMT2ASMN1; SMN2MEN1CYP2C19PIN1 | |
| SCHEMBL10965186 | 0.68 | CYP19A1 (0.41) | KMT2AMEN1CYP1A2CYP2C19PIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4450169-A | PESTICIDES; NEMATOCIDES; FUNGICIDES; MITICIDES; REPELLANTS | ROUSSEL UCLAF (FR) | 1984-05-22 | — | — | US | disclosed |