Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 10/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 9/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | QPCT | Q16769 | 1/20 | 0.43 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.43 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11493648 | 0.76 | TBXAS1 (0.66) | TBXAS1CYP19A1CYP11B1MEN1KMT2A | |
| SCHEMBL11049464 | 0.76 | TBXAS1 (0.56) | TBXAS1CYP19A1CYP11B1MEN1KMT2A | |
| SCHEMBL11053962 | 0.75 | TBXAS1 (0.71) | TBXAS1CYP19A1CYP11B1MEN1KMT2A | |
| SCHEMBL8583810 | 0.74 | TBXAS1 (0.45) | TBXAS1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL8582561 | 0.73 | TBXAS1 (0.58) | TBXAS1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL11494432 | 0.73 | TBXAS1 (0.62) | TBXAS1CYP19A1CYP11B1MEN1KMT2A | |
| SCHEMBL11048258 | 0.73 | FNTA (0.51) | — | |
| SCHEMBL11486551 | 0.73 | TBXAS1 (0.68) | TBXAS1CYP19A1CYP11B1MEN1KMT2A | |
| SCHEMBL11346119 | 0.73 | TBXAS1 (1.00) | TBXAS1CYP19A1CYP11B1MEN1KMT2A | |
| SCHEMBL11355457 | 0.72 | CYP19A1 (0.62) | TBXAS1CYP19A1CYP11B1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4451472-A | ANTITHROMBOSIS AND ANTIISCHEMIC AGENTS, AND TREATMENT OF VASCULAR COMPLICATIONS OF DIAMETES | PFIZER INC. (US) | 1984-05-29 | — | — | US | disclosed |
| US-4451472-A | ANTITHROMBOSIS AND ANTIISCHEMIC AGENTS, AND TREATMENT OF VASCULAR COMPLICATIONS OF DIAMETES | PFIZER INC. (US) | 1984-05-29 | — | — | US | disclosed |