Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 7/20 | 0.51 |
| ▸ | FNTB | P49356 | 7/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | VKORC1 | Q9BQB6 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10806686 | 0.78 | FNTA (0.45) | FNTAFNTBKDM4EALDH1A1MAPK10 | |
| SCHEMBL11049470 | 0.76 | TAAR1 (0.43) | KDM4EALDH1A1 | |
| SCHEMBL11048261 | 0.75 | TBXAS1 (0.54) | FNTAFNTBVKORC1PKMMAPK10 | |
| SCHEMBL10806849 | 0.74 | ATM (0.54) | KDM4EALDH1A1 | |
| SCHEMBL8582781 | 0.74 | TBXAS1 (0.39) | KDM4EIDO1NAPRT | |
| SCHEMBL6756295 | 0.73 | KDM4E (0.65) | KDM4EALDH1A1 | |
| SCHEMBL11049461 | 0.73 | TBXAS1 (0.57) | — | |
| SCHEMBL11037967 | 0.71 | FNTA (0.47) | FNTAFNTBKDM4EVKORC1PKM | |
| SCHEMBL6341806 | 0.71 | TBXAS1 (0.54) | FNTAFNTBVKORC1PKMMAPK10 | |
| SCHEMBL7745979 | 0.71 | KDM4E (0.57) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4451472-A | ANTITHROMBOSIS AND ANTIISCHEMIC AGENTS, AND TREATMENT OF VASCULAR COMPLICATIONS OF DIAMETES | PFIZER INC. (US) | 1984-05-29 | — | — | US | disclosed |
| US-4451472-A | ANTITHROMBOSIS AND ANTIISCHEMIC AGENTS, AND TREATMENT OF VASCULAR COMPLICATIONS OF DIAMETES | PFIZER INC. (US) | 1984-05-29 | — | — | US | disclosed |