Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 3/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11358850 | 0.77 | L3MBTL1 (0.48) | L3MBTL1KMT2ASMN1; SMN2ADORA3ADORA2A | |
| SCHEMBL2642653 | 0.77 | GRM5 (0.44) | L3MBTL1KMT2ASMN1; SMN2ADORA3ADORA2A | |
| SCHEMBL11350463 | 0.77 | L3MBTL1 (0.62) | L3MBTL1KMT2ASMN1; SMN2KDM4ELMNA | |
| SCHEMBL11474686 | 0.76 | SMN1; SMN2 (0.45) | L3MBTL1KMT2ASMN1; SMN2ADORA3ADORA2A | |
| SCHEMBL2642974 | 0.76 | L3MBTL1 (0.43) | L3MBTL1KMT2ASMN1; SMN2ADORA3ADORA2A | |
| SCHEMBL2642608 | 0.76 | L3MBTL1 (0.43) | L3MBTL1KMT2ASMN1; SMN2ADORA3ADORA2A | |
| SCHEMBL2642976 | 0.76 | L3MBTL1 (0.43) | L3MBTL1KMT2ASMN1; SMN2ADORA3ADORA2A | |
| SCHEMBL2642609 | 0.76 | PIK3CG (0.53) | L3MBTL1KMT2ASMN1; SMN2ADORA3ADORA2A | |
| SCHEMBL2642652 | 0.76 | L3MBTL1 (0.43) | L3MBTL1KMT2ASMN1; SMN2ADORA3ADORA2A | |
| SCHEMBL5609133 | 0.73 | KDM1A (0.46) | L3MBTL1ADORA2AKDM4EHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4438277-A | Hydronaphthalene derivatives | SANKYO COMPANY, LIMITED (JP) | 1984-03-20 | — | — | US | disclosed |
| US-4361515-A | Antihyperlipemic dihydro-ML-236B derivatives, their preparation and use | SANKYO COMPANY, LIMITED (JP) | 1982-11-30 | — | — | US | disclosed |