Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.43 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.43 |
| ▸ | TYMS | P04818 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6890110 | 0.83 | MAPT (0.51) | TSHRLMNAMAPTMEN1KMT2A | |
| SCHEMBL28973301 | 0.80 | L3MBTL1 (0.43) | MAPTKMT2APOLBCA12CA1 | |
| SCHEMBL1066872 | 0.80 | MAPT (0.41) | TSHRLMNAMAPTMEN1KMT2A | |
| SCHEMBL1066869 | 0.80 | MAPT (0.41) | TSHRLMNAMAPTMEN1KMT2A | |
| SCHEMBL17698892 | 0.79 | GLA (0.52) | TSHRLMNAMAPTMEN1KMT2A | |
| SCHEMBL8516383 | 0.79 | TSHR (0.52) | TSHRLMNAMAPTMEN1KMT2A | |
| SCHEMBL5706075 | 0.78 | MAPT (0.47) | TSHRMAPTMEN1KMT2ATYMS | |
| SCHEMBL19608969 | 0.77 | TSHR (0.58) | TSHRLMNAMAPTMEN1KMT2A | |
| SCHEMBL27659891 | 0.77 | L3MBTL1 (0.44) | LMNAMAPTMEN1KMT2APOLB | |
| SCHEMBL1069487 | 0.77 | MAPT (0.39) | TSHRLMNAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4452811-A | VASODILATORS | FIDIA S.P.A. (IT) | 1984-06-05 | — | — | US | disclosed |
| US-4296039-A | REACTING 2-HALORESORCINOLS OR THEIR MONOETHERS WITH BETA-KETO ESTERS | FIDIA S.P.A. (IT) | 1981-10-20 | — | — | US | disclosed |