SCHEMBL28973301

SCHEMBL28973301

CCC(=O)Oc1cccc(OC)c1Cl

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.43
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA7 P43166 1/20 0.43
CA9 Q16790 1/20 0.43
CA14 Q9ULX7 1/20 0.43
JAK2 O60674 1/20 0.42
FGFR1 P11362 1/20 0.42
VCP P55072 1/20 0.42
ALDH1A1 P00352 2/20 0.41
MAPT P10636 1/20 0.41
ACHE P22303 2/20 0.41
ALOX15 P16050 1/20 0.41
ESR1 P03372 2/20 0.40
HIF1A Q16665 2/20 0.40
TAS1R3 Q7RTX0 1/20 0.39
TAS1R1 Q7RTX1 1/20 0.39
ELANE P08246 1/20 0.39
ATM Q13315 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27659891 0.87 L3MBTL1 (0.44) L3MBTL1CA12CA1CA2CA7
SCHEMBL1261928 0.84 HTR1D (0.46) L3MBTL1ALDH1A1ACHEALOX15ESR1
SCHEMBL15842130 0.83 ACHE (0.46) L3MBTL1ALDH1A1MAPTACHEALOX15
SCHEMBL30883175 0.82 MAPT (0.57) L3MBTL1CA12CA1CA2CA7
SCHEMBL362210 0.82 MAPT (0.57) L3MBTL1CA12CA1CA2CA7
SCHEMBL1159881 0.81 ESR1 (0.42) L3MBTL1ALDH1A1ACHEALOX15ESR1
SCHEMBL1261193 0.81 ACHE (0.43) ALDH1A1MAPTACHEALOX15ESR1
SCHEMBL15547744 0.81 NFE2L2 (0.47) L3MBTL1CA12CA1CA2CA7
SCHEMBL14471561 0.81 NFE2L2 (0.51) L3MBTL1CA12CA1CA2CA7
SCHEMBL27669744 0.81 KDM4E (0.44) L3MBTL1CA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115515575-A Tyrosine derivatives for the modulation of cancer 迪美公司 2022-12-23 CN claimed