Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | RORA | P35398 | 1/20 | 0.48 |
| ▸ | RORC | P51449 | 1/20 | 0.48 |
| ▸ | RORB | Q92753 | 1/20 | 0.48 |
| ▸ | CTSV | O60911 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | GPR3 | P46089 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29854556 | 0.99 | KDM4E (0.50) | KDM4EALDH1A1MAPTL3MBTL1NPC1 | |
| SCHEMBL11049850 | 0.99 | KDM4E (0.50) | KDM4EALDH1A1MAPTL3MBTL1NPC1 | |
| SCHEMBL52641 | 0.99 | KDM4E (0.50) | KDM4EALDH1A1MAPTL3MBTL1NPC1 | |
| SCHEMBL195467 | 0.99 | KDM4E (0.50) | KDM4EALDH1A1MAPTL3MBTL1NPC1 | |
| SCHEMBL11053472 | 0.96 | KDM4E (0.53) | KDM4EALDH1A1MAPTL3MBTL1NPC1 | |
| SCHEMBL10791944 | 0.92 | RORA (0.46) | KDM4EALDH1A1MAPTL3MBTL1NPC1 | |
| SCHEMBL725252 | 0.90 | KDM4E (0.55) | KDM4EALDH1A1MAPTL3MBTL1NPC1 | |
| SCHEMBL14797740 | 0.88 | RORA (0.46) | KDM4EALDH1A1RORARORCRORB | |
| SCHEMBL18242408 | 0.87 | ALDH1A1 (0.46) | KDM4EALDH1A1MAPTL3MBTL1NPC1 | |
| SCHEMBL22345133 | 0.87 | RORA (0.48) | KDM4EALDH1A1RORARORCRORB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0036075-B1 | MIXTURES BASED ON AROMATIC-ALIPHATIC KETONES, THEIR USE AS PHOTOINITIATORS AND PHOTOPOLYMERISABLE SYSTEMS CONTAINING SUCH MIXTURES | MERCK PATENT GmbH (DE) | 1984-06-06 | — | — | EP | disclosed |
| US-4434035-A | Mixtures of aromatic-aliphatic ketones as photoinitiators and photopolymerizable systems containing them | Merck Patent Gesellschaft mit beschr/a/ nkter Haftung (DE) | 1984-02-28 | — | — | US | disclosed |
| US-4390453-A | DISCOLORATION INHIBITION; ULTRAVIOLET HARDENING OF ACRYLIC INKS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1983-06-28 | — | — | US | disclosed |
| EP-0036075-A1 | Mixtures based on aromatic-aliphatic ketones, their use as photoinitiators and photopolymerisable systems containing such mixtures | MERCK PATENT GmbH (DE) | 1981-09-23 | — | — | EP | disclosed |