SCHEMBL11049883

SCHEMBL11049883

CCC(=C(C#N)C(=O)O)c1ccc(O)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 11/20 0.55
ESR2 Q92731 6/20 0.55
ALDH1A1 P00352 2/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
PGR P06401 2/20 0.55
PTGS2 P35354 2/20 0.55
MEN1 O00255 1/20 0.55
NR1I2 O75469 1/20 0.55
USP2 O75604 1/20 0.55
LMNA P02545 1/20 0.55
NR3C1 P04150 1/20 0.55
TP53 P04637 1/20 0.55
CYP1A2 P05177 1/20 0.55
FYN P06241 1/20 0.55
CHRM2 P08172 1/20 0.55
ADRB1 P08588 1/20 0.55
CYP3A4 P08684 1/20 0.55
ADRA2A P08913 1/20 0.55
ADORA3 P0DMS8 1/20 0.55
AR P10275 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29119424 0.88 ALDH1A1 (0.44) ESR1ESR2ALDH1A1SMN1; SMN2PGR
SCHEMBL19357469 0.86 ALDH1A1 (0.47) ESR1ESR2ALDH1A1SMN1; SMN2PGR
SCHEMBL19357468 0.86 ALDH1A1 (0.47) ESR1ESR2ALDH1A1SMN1; SMN2PGR
SCHEMBL17387472 0.85 HTT (0.41) ESR1ESR2ALDH1A1SMN1; SMN2PGR
SCHEMBL17387473 0.85 HTT (0.41) ESR1ESR2ALDH1A1SMN1; SMN2PGR
SCHEMBL2879590 0.85 GSK3B (0.45) ESR1ALDH1A1MEN1MAPTSLC6A3
SCHEMBL2879593 0.85 GSK3B (0.45) ESR1ALDH1A1MEN1MAPTSLC6A3
SCHEMBL27352443 0.83 NR1I2 (0.59) ESR1SMN1; SMN2PTGS2NR1I2KMT2A
SCHEMBL226431 0.83 NR1I2 (0.59) ESR1SMN1; SMN2PTGS2NR1I2KMT2A
SCHEMBL15991618 0.77 ALDH1A1 (0.47) ESR1ESR2ALDH1A1SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117192672-A Resin film, method for producing resin film, and method for producing phase difference film 日东电工株式会社 2023-12-08 CN disclosed
CN-117192671-A Polarizing plate with phase difference layer 日东电工株式会社 2023-12-08 CN disclosed
US-20180203162-A1 Method for producing a reflection-reducing layer system and reflection-reducing layer system FRAUNHOFER GES FORSCHUNG (DE) 2018-07-19 US disclosed
US-9939556-B2 Method for producing a reflection-reducing layer system and reflection-reducing layer system Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2018-04-10 US disclosed
EP-3051321-A1 METHOD FOR PRODUCING A REFLECTION-REDUCING LAYER SYSTEM AND REFLECTION-REDUCING COATING SYSTEM Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2016-08-03 EP disclosed
US-20160216409-A1 Method for Producing a Reflection-Reducing Layer System and Reflection-Reducing Layer System FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 2016-07-28 US disclosed
US-4431726-A WHICH IS A POLYMER LATEX FUJI PHOTO FILM CO., LTD. (JP) 1984-02-14 US disclosed