SCHEMBL226431

SCHEMBL226431

CCC(=C(C#N)C(=O)O)c1ccc(OC)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1I2 O75469 1/20 0.59
CA1 P00915 4/20 0.47
CA2 P00918 4/20 0.47
PTGS2 P35354 1/20 0.46
ESR1 P03372 1/20 0.45
RECQL P46063 1/20 0.45
KMT2A Q03164 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
HIF1A Q16665 1/20 0.45
CES2 O00748 2/20 0.44
CES1 P23141 2/20 0.44
HDAC3 O15379 2/20 0.43
HDAC1 Q13547 2/20 0.43
HDAC2 Q92769 2/20 0.43
HDAC8 Q9BY41 2/20 0.43
GSK3B P49841 1/20 0.42
HDAC4 P56524 1/20 0.42
HDAC7 Q8WUI4 1/20 0.42
HDAC10 Q969S8 1/20 0.42
HDAC11 Q96DB2 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27352443 1.00 NR1I2 (0.59) NR1I2CA1CA2PTGS2ESR1
SCHEMBL10591928 0.88 NR1I2 (0.47) NR1I2CA1CA2PTGS2SMN1; SMN2
SCHEMBL246300 0.85 PTGS2 (0.46) NR1I2CA1CA2PTGS2HDAC3
SCHEMBL4964670 0.84 CA1 (0.44) NR1I2CA1CA2KMT2ASMN1; SMN2
SCHEMBL29119424 0.84 ALDH1A1 (0.44) NR1I2CA1CA2PTGS2ESR1
SCHEMBL9214719 0.84 PTGS2 (0.46) NR1I2PTGS2HDAC3HDAC1HDAC2
SCHEMBL11049883 0.83 ESR1 (0.55) NR1I2PTGS2ESR1KMT2ASMN1; SMN2
SCHEMBL19357468 0.82 ALDH1A1 (0.47) PTGS2ESR1SMN1; SMN2CES2CES1
SCHEMBL19357469 0.82 ALDH1A1 (0.47) PTGS2ESR1SMN1; SMN2CES2CES1
SCHEMBL17387473 0.81 HTT (0.41) NR1I2CA1CA2PTGS2ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 862 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260139087-A1 COMPOUND, POLYMER, LIGHT STABILIZER COMPOSITION, RESIN COMPOSITION, COATING MATERIAL COMPOSITION, ARTICLE, SEALING MATERIAL, MOLDED ARTICLE, METHOD FOR PRODUCING WEATHER-RESISTANT RESIN COMPOSITION, AND METHOD FOR IMPROVING WEATHER RESISTANCE OF SYNTHETIC RESIN ADEKA CORPORATION (JP) 2026-05-21 US disclosed
EP-4745198-A1 RESIN COMPOSITION, MOLDED ARTICLE, RESIN ADDITIVE COMPOSITION, METHOD FOR PRODUCING RESIN COMPOSITION, METHOD FOR IMPROVING CRYSTALLINITY OF CRYSTALLINE RESIN, AND MATERIAL FOR RESIN ADDITIVE COMPOSITION ADEKA CORPORATION (JP) 2026-05-20 EP disclosed
US-12624265-B2 Antistatic agent, antistatic composition comprising same, antistatic resin composition comprising same, and molded article thereof ADEKA CORPORATION (JP) 2026-05-12 US disclosed
EP-4729581-A1 PLASTICIZER, COMPOSITION, AND MOLDED ARTICLE ADEKA CORPORATION (JP) 2026-04-22 EP disclosed
EP-3405520-B1 POLYAMIDE COMPOSITION CONTAINING A METALLIC PIGMENT TICONA LLC (US) 2026-02-25 EP disclosed
US-12540122-B2 Nucleating agent, synthetic-resin composition containing same, and molded object thereof ADEKA CORPORATION (JP) 2026-02-03 US disclosed
US-12540229-B2 Flame-retardant composition and flame-retardant synthetic resin composition ADEKA CORPORATION (JP) 2026-02-03 US disclosed
EP-4678699-A1 RESIN ADDITIVE, COMPOSITION, MOLDED ARTICLE AND COMPOUND ADEKA CORPORATION (JP) 2026-01-14 EP disclosed
US-20260002014-A1 RESIN COMPOSITION AND MOLDED ARTICLE THEREOF ADEKA CORPORATION (JP) 2026-01-01 US disclosed
WO-2025245330-A1 PHOSPHITE POLYMER PROCESSING AID AND PROCESS OF PREPARING A THERMOPLASTIC POLYMER COMPOSITION SI GROUP, INC. (US) 2025-11-27 WO disclosed
US-5767179-A INFRARED ABSORBERS FUJI CHEMICAL INDUSTRY CO., LTD. (JP) 1998-06-16 US disclosed
EP-0813571-A1 FLAME RETARDANT FOR STYRENE RESIN AND RESIN COMPOSITION COMPRISING THE SAME Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1997-12-29 EP disclosed
EP-0778241-A1 NOVEL COMPOSITE HYDROXIDE/CONDENSED SILICATES, PROCESS FOR THE PRODUCTION THEREOF, INFRARED ABSORBER, AND AGRICULTURAL FILM FUJI CHEMICAL INDUSTRY CO., LTD. (JP) 1997-06-11 EP disclosed
EP-0767215-A1 AROMATIC POLYCARBONATE-STYRENE POLYMER RESIN COMPOSITION Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1997-04-09 EP disclosed
EP-0761756-A1 STABILIZER FOR HALOGEN-CONTAINING RESINS AND PROCESS FOR THE PREPARATION THEREOF, HALOGEN-CONTAINING RESIN COMPOSITION, AND COMPOSITE HYDROXIDE SALT FUJI CHEMICAL INDUSTRY CO., LTD. (JP) 1997-03-12 EP disclosed
WO-1996027637-A1 FLAME RETARDANT FOR STYRENE RESIN AND RESIN COMPOSITION COMPRISING THE SAME ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1996-09-12 WO disclosed
EP-0336606-B1 COMPOSITION OF STABILIZED SYNTHETIC RESIN ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 1993-09-08 EP disclosed
US-4885326-A 2,2'-ALKYLIDENE-BISPHENOL CYCLIC ALKYLPHOSPHITE AND 3,5-DIALKYL-4-HYDROXYPHENYLPROPIONIC ACID ESTER; HEAT, LIGHT, AND OXIDATION RESISTANCE ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1989-12-05 US disclosed
US-4525504-A 1,4-CYCLOHEXANDEICARBOXYLIC ACID AND 2,2,4,4-TETRAMETHYL-1,3-CYCLOBUTANEDIOL, UV AND HINDERED AMINE STABILIZERS EASTMAN KODAK COMPANY (US) 1985-06-25 US disclosed
US-4524165-A 1,4-CYCLOHEXANEDICARBOXYLIC ACID AND 1,4-CYCLOHEXANE DIOL MONOMERS; POLYALKYLENE GLCOLS; STABILIZER MIXTURE EASTMAN KODAK COMPANY (US) 1985-06-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12540122-B2 Nucleating agent, synthetic-resin composition containing same, and molded object thereof NXF1, NAP1L1, POT1 NR1I2 1662/4885CA1 4318/4885CA2 4357/4885
US-20260002014-A1 RESIN COMPOSITION AND MOLDED ARTICLE THEREOF NXF1, NOP2, RTF1 NR1I2 1190/4885CA1 1519/4885CA2 2253/4885
US-20260139087-A1 COMPOUND, POLYMER, LIGHT STABILIZER COMPOSITION, RESIN COMPOSITION, COATING MATERIAL COMPOSITION, ARTICLE, SEALING MATERIAL, MOLDED ARTICLE, METHOD FOR PRODUCING WEATHER-RESISTANT RESIN COMPOSITION, AND METHOD FOR IMPROVING WEATHER RESISTANCE OF SYNTHETIC RESIN SEM1, RAD51, SUN2 NR1I2 2122/4885CA1 865/4885CA2 1764/4885
US-12624265-B2 Antistatic agent, antistatic composition comprising same, antistatic resin composition comprising same, and molded article thereof SORD, SUCLA2, SUCLG1 NR1I2 3689/4885CA1 8/4885CA2 119/4885
US-12540229-B2 Flame-retardant composition and flame-retardant synthetic resin composition PAF1, RER1, POLR2A NR1I2 2021/4885CA1 1749/4885CA2 1251/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.