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SCHEMBL11049891

SCHEMBL11049891

CC(C)C(=O)Nc1nnc(S(N)(=O)=O)s1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA1 P00915 13/20 1.00
▸ CA2 P00918 13/20 1.00
▸ CA4 P22748 8/20 1.00
▸ CA9 Q16790 8/20 1.00
▸ CA12 O43570 3/20 0.69
▸ CA3 P07451 3/20 0.69
▸ CA6 P23280 3/20 0.69
▸ CA5A P35218 3/20 0.69
▸ CA7 P43166 3/20 0.69
▸ CA13 Q8N1Q1 3/20 0.69
▸ CA14 Q9ULX7 3/20 0.69
▸ CA5B Q9Y2D0 3/20 0.69
▸ MEN1 O00255 1/20 0.69
▸ CA11 O75493 1/20 0.69
▸ THRB P10828 1/20 0.69
▸ BLM P54132 1/20 0.69
▸ KMT2A Q03164 1/20 0.69
▸ SMN1; SMN2 Q16637 1/20 0.69
▸ TDP1 Q9NUW8 1/20 0.69
▸ MAPT P10636 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19383010 0.89 CA1 (0.80) CA1CA2CA4CA9CA12
SCHEMBL9403512 0.89 CA1 (0.80) CA1CA2CA4CA9CA12
Bromide SCHEMBL9403550 0.88 CA1 (0.78) CA1CA2CA4CA9CA12
SCHEMBL19382585 0.85 CA1 (0.74) CA1CA2CA4CA9CA12
SCHEMBL17850506 0.84 CA1 (0.72) CA1CA2CA4CA9CA12
SCHEMBL19382598 0.83 CA1 (0.70) CA1CA2CA4CA9CA12
Acetazolamide SCHEMBL2557036 0.81 CA1 (1.00) CA1CA2CA4CA9CA12
Acetazolamide SCHEMBL23219 0.81 CA1 (1.00) CA1CA2CA4CA9CA12
SCHEMBL19382592 0.81 CA1 (0.68) CA1CA2CA4CA9CA12
SCHEMBL22118514 0.81 CA1 (0.73) CA1CA2CA4CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115399322-A Aqueous herbicidal concentrate 孟山都技术公司 2022-11-29 — — CN claimed
CN-114760843-A Herbicidal composition UPL有限责任公司 2022-07-15 — — CN claimed
US-4424227-A Gastric cytoprotection with heterocyclic sulfonamides THE UPJOHN COMPANY (US) 1984-01-03 — — US claimed
US-12378211-B2 Carbonic anhydrase inhibitors and antibiotics against multidrug resistant bacteria PURDUE RESEARCH FOUNDATION (US) 2025-08-05 — — US disclosed
US-20230381324-A1 SMALL MOLECULE DRUG CONJUGATES EIDGENOESSICHE TECHNISCHE HOCHSCHULE ZURICH (CH) 2023-11-30 — — US disclosed
US-20230381324-A1 SMALL MOLECULE DRUG CONJUGATES EIDGENOESSICHE TECHNISCHE HOCHSCHULE ZURICH (CH) 2023-11-30 — — US disclosed
CN-114760843-A Herbicidal composition UPL有限责任公司 2022-07-15 — — CN disclosed
US-20220213047-A1 CARBONIC ANHYDRASE INHIBITORS FOR TREATMENT OF NEISSERIA GONORRHOEAE INFECTION PURDUE RESEARCH FOUNDATION (US) 2022-07-07 — — US disclosed
US-20220023277-A1 CARBONIC ANHYDRASE TARGETING AGENTS AND METHODS OF USING SAME VISEN MEDICAL, INC. 2022-01-27 — — US disclosed
CN-113951258-A Selective weed control using D-napropamide UPL 有限公司 2022-01-21 — — CN disclosed
US-11059802-B2 Carbonic anhydrase targeting agents and methods of using same VISEN MEDICAL, INC. (US) 2021-07-13 — — US disclosed
US-10016511-B2 Small molecule drug conjugates ETH ZURICH (CH) 2018-07-10 — — US disclosed
US-9884122-B2 Small molecule drug conjugates ETH ZURICH (CH) 2018-02-06 — — US disclosed
US-9884122-B2 Small molecule drug conjugates ETH ZURICH (CH) 2018-02-06 — — US disclosed
US-20170224831-A1 Small Molecule Drug Conjugates ETH ZURICH (CH) 2017-08-10 — — US disclosed
US-20170224831-A1 Small Molecule Drug Conjugates ETH ZURICH (CH) 2017-08-10 — — US disclosed
US-20170035892-A1 Small Molecule Drug Conjugates ETH ZURICH (CH) 2017-02-09 — — US disclosed
US-20170035892-A1 Small Molecule Drug Conjugates ETH ZURICH (CH) 2017-02-09 — — US disclosed
US-20120321563-A1 Carbonic Anhydrase Targeting Agents and Methods of Using Same VISEN MEDICAL, INC. 2012-12-20 — — US disclosed
US-4424227-A Gastric cytoprotection with heterocyclic sulfonamides THE UPJOHN COMPANY (US) 1984-01-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230381324-A1 SMALL MOLECULE DRUG CONJUGATES CA9, CA12, CA2 CA1 10/4885CA2 3/4885CA4 4/4885
US-20120321563-A1 Carbonic Anhydrase Targeting Agents and Methods of Using Same CA4, CA12, CA9 CA1 7/4885CA2 4/4885CA4 1/4885
US-20170035892-A1 Small Molecule Drug Conjugates CA9, CA11, CA4 CA1 6/4885CA2 11/4885CA4 3/4885
US-12378211-B2 Carbonic anhydrase inhibitors and antibiotics against multidrug resistant bacteria CA9, CA2, CA4 CA1 9/4885CA2 2/4885CA4 3/4885
US-11059802-B2 Carbonic anhydrase targeting agents and methods of using same CA4, CA12, CA9 CA1 7/4885CA2 4/4885CA4 1/4885
US-10016511-B2 Small molecule drug conjugates CA9, CA12, CA2 CA1 10/4885CA2 3/4885CA4 4/4885
US-20220023277-A1 CARBONIC ANHYDRASE TARGETING AGENTS AND METHODS OF USING SAME CA4, CA12, CA9 CA1 7/4885CA2 4/4885CA4 1/4885
US-20220213047-A1 CARBONIC ANHYDRASE INHIBITORS FOR TREATMENT OF NEISSERIA GONORRHOEAE INFECTION CA4, CA7, CA9 CA1 11/4885CA2 6/4885CA4 1/4885
US-20170224831-A1 Small Molecule Drug Conjugates CA9, CA12, CA2 CA1 10/4885CA2 3/4885CA4 4/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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