SCHEMBL110499

SCHEMBL110499

Nc1ccc(Br)c(F)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4653670 1.00 KDM1A (0.45)
SCHEMBL29531746 0.79
SCHEMBL148505 0.79
SCHEMBL31287823 0.77 MAPT (0.55)
SCHEMBL22914553 0.77 RAB9A (0.54)
SCHEMBL29407502 0.75
SCHEMBL632670 0.75
SCHEMBL14413 0.75
SCHEMBL29393564 0.75
SCHEMBL9701 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1600 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119707773-A Preparation method and application of maleimide structure-containing compound 中国农业大学 2025-03-28 CN claimed
CN-111978209-B Synthesis method of tedizolid phosphate intermediate 3-fluoro-4-bromoaniline 成都美域高制药有限公司 2023-05-30 CN claimed
CN-115873036-A Synthetic method of tedizolid phosphate 中国药科大学 2023-03-31 CN claimed
CN-113248411-A Preparation method of halogenated aromatic sulfonyl chloride 南京爱可德夫科技开发有限公司 2021-08-13 CN claimed
CN-112827368-A Anti-pollution reverse osmosis membrane and preparation method thereof 中化(宁波)润沃膜科技有限公司 2021-05-25 CN claimed
CN-111978209-A Synthetic method of tedizolid phosphate intermediate 3-fluoro-4-bromoaniline 成都美域高制药有限公司 2020-11-24 CN claimed
CN-108314647-B Preparation method of quinoline-2-formic acid and quinoline-2-formic acid derivative 华中科技大学 2020-06-26 CN claimed
CN-107021883-B Synthetic method and application of polysubstituted biphenyl halide liquid crystal intermediate HEBEI MAISON CHEMICAL CO., LTD. (CN) 2019-12-10 CN claimed
EP-1773768-B1 PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS EXELIXIS INC (US) 2018-08-22 EP claimed
WO-2016009401-A2 PREPARATION OF TEDIZOLID PHOSPHATE DR. REDDY'S LABORATORIES LIMITED (IN) 2016-01-21 WO claimed
WO-2007130712-A1 SUBSTITUTED DIPIPERIDINE AS CCR2 ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES JANSSEN PHARMACEUTICA, NV (BE) 2007-11-15 WO claimed
JP-2007523865-A 2007-08-23 JP claimed
US-20070197590-A1 SUBSTITUTED DIPIPERIDINE CCR2 ANTAGONISTS JANSSEN PHARMACEUTCA N.V. (BE) 2007-08-23 US claimed
EP-1773768-A2 PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS Exelixis, Inc. (US) 2007-04-18 EP claimed
US-20060276496-A1 Anti-Cytokine Heterocyclic Compounds BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) 2006-12-07 US claimed
US-7129235-B2 Amides useful for treating pain ABBOTT LABORATORIES (US) 2006-10-31 US claimed
EP-1646621-A2 NOVEL AZAHETEROCYCLIC AMIDES USEFUL FOR TREATING PAIN Abbott Laboratories (US) 2006-04-19 EP claimed
WO-2006012642-A2 PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS EXELIXIS, INC. (US) 2006-02-02 WO claimed
US-20050080095-A1 administering a therapeuitcally effective amount of 3'-(trifluoromethyl)-N-{4-[(trifluoromethyl)sulfonyl]phenyl}-3,6-dihydro-2H-1,2'-bipyridine-4-carboxamide; antagonists of vanilloid receptor subtype I ABBVIE INC. 2005-04-14 US claimed
WO-2005007642-A2 NOVEL AZAHETEROCYCLIC AMIDES USEFUL FOR TREATING PAIN ABBOTT LABORATORIES (US) 2005-01-27 WO claimed