⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29393564 | 1.00 | — | — | |
| Iodide SCHEMBL31415556 | 0.97 | MAPT (0.39) | — | |
| Methane SCHEMBL27626480 | 0.97 | MAPT (0.39) | — | |
| SCHEMBL1266210 | 0.89 | ALDH1A1 (0.54) | — | |
| SCHEMBL27598943 | 0.80 | HTR2A (0.36) | — | |
| SCHEMBL29487496 | 0.79 | — | — | |
| SCHEMBL29415472 | 0.79 | — | — | |
| SCHEMBL33738 | 0.79 | — | — | |
| SCHEMBL712310 | 0.79 | TSHR (0.48) | — | |
| SCHEMBL33161 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3775 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240270970-A1 | METHOD OF MANIPULATING HYDROPHILICITY AND HYDROPHOBICITY OF CONVENTIONAL DYE MOLECULES FOR TRACER APPLICATIONS | SAUDI ARABIAN OIL COMPANY (SA) | 2024-08-15 | — | — | US | claimed |
| CN-118183708-A | Method for preparing fluorocarbon material by using fluorine-containing polymer | 重庆大学锂电及新材料遂宁研究院 | 2024-06-14 | — | — | CN | claimed |
| CN-118184650-A | 6- (1H-pyrrolo [2,3-b ] pyridin-3-yl) quinazoline-4-amine derivative, and preparation method and application thereof | 中国人民解放军北部战区总医院 | 2024-06-14 | — | — | CN | claimed |
| CN-117843679-A | Fluorine-containing biphosphine compound and preparation method thereof | 四川轻化工大学 | 2024-04-09 | — | — | CN | claimed |
| CN-117510421-B | Fluorine-containing benzotriazolyl fluorescent compound for optical transfer film and synthesis method thereof | 河北美星化工有限公司 | 2024-04-05 | — | — | CN | claimed |
| CN-117510421-A | Fluorine-containing benzotriazolyl fluorescent compound for optical transfer film and synthesis method thereof | 河北美星化工有限公司 | 2024-02-06 | — | — | CN | claimed |
| CN-117402140-A | Quinolone indole compound and preparation method and application thereof | 西南大学 | 2024-01-16 | — | — | CN | claimed |
| CN-116730795-B | Synthesis method of trifluoro-phenylacetic acid intermediate 1,2, 4-trifluoro-benzene | 山东国邦药业有限公司 | 2023-10-27 | — | — | CN | claimed |
| CN-116730795-A | Synthesis method of trifluoro-phenylacetic acid intermediate 1,2, 4-trifluoro-benzene | 山东国邦药业有限公司 | 2023-09-12 | — | — | CN | claimed |
| CN-116606214-A | Synthesis method of 3, 4-difluoroaniline | 山东国邦药业有限公司 | 2023-08-18 | — | — | CN | claimed |
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | claimed |
| WO-2002020483-A1 | PIPERIDINE DERIVATIVES FOR USE 2,3-OXIDOSQUALENE-LANOSTEROL CYCLASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2002-03-14 | — | — | WO | claimed |
| WO-2002012442-A2 | HETEROCYCLIC COMPOUNDS AS LIGANDS OF THE GABAA RECEPTOR | NEUROGEN CORPORATION (US) | 2002-02-14 | — | — | WO | claimed |
| EP-0667337-B1 | Method for preparing fluoroanilines | CLARIANT GMBH (DE) | 1998-01-21 | — | — | EP | claimed |
| US-5498794-A | Process for preparing fluoroanilines | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-03-12 | — | — | US | claimed |
| EP-0667337-A1 | Method for preparing fluoroanilines | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-08-16 | — | — | EP | claimed |
| EP-0527154-A1 | PROCESS FOR PREPARING 3,4-DIFLUOROANILINE | Pfizer Hospital Products Group, Inc. (US) | 1993-02-17 | — | — | EP | claimed |
| WO-1991017138-A1 | PROCESS FOR PREPARING 3,4-DIFLUOROANILINE | PFIZER INC. (US) | 1991-11-14 | — | — | WO | claimed |
| US-4833270-A | Process for preparing 2-chloro-4,5-difluorobenzoic acid | AMERICAN CYANAMID COMPANY (US) | 1989-05-23 | — | — | US | claimed |
| US-4343951-A | Method for the preparation of fluoroaniline | HOOKER CHEMICALS & PLASTICS CORP. (US) | 1982-08-10 | — | — | US | claimed |