Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.37 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TIMP3 | P35625 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11055084 | 0.89 | ENPP2 (0.40) | KDM4EGPR17KMT2AMEN1USP2 | |
| SCHEMBL10541404 | 0.88 | ENPP2 (0.41) | KDM4EKMT2AMEN1TIMP3TDP1 | |
| SCHEMBL11053268 | 0.87 | CASP6 (0.49) | KMT2AMEN1USP2ALDH1A1TIMP3 | |
| SCHEMBL11050204 | 0.85 | NT5E (0.44) | KMT2AMEN1USP2ALDH1A1TIMP3 | |
| SCHEMBL11046533 | 0.85 | CASP6 (0.45) | GPR17KMT2AMEN1USP2ALDH1A1 | |
| SCHEMBL11050559 | 0.85 | ENPP2 (0.45) | GPR17KMT2AMEN1USP2ALDH1A1 | |
| SCHEMBL11049471 | 0.84 | ENPP2 (0.40) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL10624886 | 0.84 | KMT2A (0.45) | KDM4EKMT2AMEN1USP2ALDH1A1 | |
| SCHEMBL11052845 | 0.84 | APEX1 (0.46) | KMT2AMEN1USP2ALDH1A1TIMP3 | |
| SCHEMBL11046935 | 0.84 | ENPP2 (0.42) | KDM4EGPR17KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4473498-A | Water-soluble, fiber-reactive organic dyestuffs containing a β-chloro-ethylsulfonyl-methyl-benzoic acid amide group | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-09-25 | — | — | US | disclosed |