SCHEMBL11050233

SCHEMBL11050233

CN(C)CCCN(CCC#N)CCCN(C)C

nearest known ligand 0.61

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LCK P06239 2/20 0.61
ALDH1A1 P00352 3/20 0.39
TSHR P16473 2/20 0.39
DNM1 Q05193 3/20 0.33
TDP1 Q9NUW8 1/20 0.32
DRD3 P35462 1/20 0.31
CYP1A2 P05177 2/20 0.30
CYP2D6 P10635 1/20 0.30
HPGD P15428 1/20 0.30
CASP1 P29466 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11344509 1.00 LCK (0.61) LCKALDH1A1TSHRDNM1TDP1
SCHEMBL10051136 0.87 LCK (0.76) LCKALDH1A1TSHRTDP1DRD3
SCHEMBL714869 0.87 LCK (0.76) LCKALDH1A1TSHRTDP1DRD3
SCHEMBL11416501 0.85 LCK (0.48) LCKALDH1A1TSHRTDP1DRD3
SCHEMBL13844443 0.85 LCK (0.73) LCKALDH1A1TSHRTDP1DRD3
SCHEMBL15591992 0.82 LCK (0.70) LCKALDH1A1TSHRTDP1DRD3
SCHEMBL2425755 0.82 LCK (0.68) LCKALDH1A1TSHRTDP1DRD3
SCHEMBL11349006 0.81 LCK (0.43) LCKTSHRCYP1A2MAPK1
SCHEMBL16639235 0.81 LCK (0.40) LCKALDH1A1TSHRDNM1TDP1
SCHEMBL15591979 0.79 LCK (0.65) LCKALDH1A1TSHRTDP1DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3303440-A1 REACTIVE AMINE CATALYSTS FOR POLYURETHANE APPLICATIONS Evonik Degussa GmbH (DE) 2018-04-11 EP claimed
US-20170247495-A1 LOW EMISSIONS POLYURETHANE FOAM MADE WITH ISOCYANATE REACTIVE AMINE CRYSTALS EVONIK OPERATIONS GMBH (DE) 2017-08-31 US claimed
EP-3191537-A1 LOW EMISSIONS POLYURETHANE FOAM MADE WITH ISOCYANATE REACTIVE AMINE CRYSTALS Evonik Degussa GmbH (DE) 2017-07-19 EP claimed
WO-2016196643-A1 REACTIVE AMINE CATALYSTS FOR POLYURETHANE APPLICATIONS AIR PRODUCTS AND CHEMICALS, INC. (US) 2016-12-08 WO claimed
US-20160347901-A1 REACTIVE AMINE CATALYSTS FOR POLYURETHANE APPLICATIONS AIR PRODUCTS AND CHEMICALS, INC. (US) 2016-12-01 US claimed
WO-2016040783-A1 LOW EMISSIONS POLYURETHANE FOAM MADE WITH ISOCYANATE REACTIVE AMINE CRYSTALS AIR PRODUCTS AND CHEMICALS, INC. (US) 2016-03-17 WO claimed
US-20160075817-A1 Low Emissions Polyurethane Foam Made with Isocyanate Reactive Amine Catalyst AIR PRODUCTS AND CHEMICALS, INC. (US) 2016-03-17 US claimed
EP-3303440-B1 REACTIVE AMINE CATALYSTS FOR POLYURETHANE APPLICATIONS EVONIK OPERATIONS GMBH (DE) 2025-08-06 EP disclosed
EP-3191537-B1 LOW EMISSIONS POLYURETHANE FOAM MADE WITH ISOCYANATE REACTIVE AMINE CATALYSTS EVONIK OPERATIONS GMBH (DE) 2024-11-06 EP disclosed
CN-115433335-A Low emission polyurethane foams made with isocyanate-reactive amine crystals 赢创运营有限公司 2022-12-06 CN disclosed
US-11208519-B2 Reactive amine catalysts for polyurethane applications EVONIK OPERATIONS GMBH (DE) 2021-12-28 US disclosed
CN-107922579-B Reactive amine catalysts for polyurethane applications 赢创运营有限公司 2021-06-08 CN disclosed
US-10421832-B2 Low emissions polyurethane foam made with isocyanate reactive amine catalysts EVONIK DEGUSSA GMBH (DE) 2019-09-24 US disclosed
EP-3191537-A1 LOW EMISSIONS POLYURETHANE FOAM MADE WITH ISOCYANATE REACTIVE AMINE CRYSTALS Evonik Degussa GmbH (DE) 2017-07-19 EP disclosed
WO-2016196643-A1 REACTIVE AMINE CATALYSTS FOR POLYURETHANE APPLICATIONS AIR PRODUCTS AND CHEMICALS, INC. (US) 2016-12-08 WO disclosed
US-20160347901-A1 REACTIVE AMINE CATALYSTS FOR POLYURETHANE APPLICATIONS AIR PRODUCTS AND CHEMICALS, INC. (US) 2016-12-01 US disclosed
WO-2016040783-A1 LOW EMISSIONS POLYURETHANE FOAM MADE WITH ISOCYANATE REACTIVE AMINE CRYSTALS AIR PRODUCTS AND CHEMICALS, INC. (US) 2016-03-17 WO disclosed
US-20160075817-A1 Low Emissions Polyurethane Foam Made with Isocyanate Reactive Amine Catalyst AIR PRODUCTS AND CHEMICALS, INC. (US) 2016-03-17 US disclosed
EP-0025142-B1 POLYQUATERNARY AMMONIUM COMPOUNDS, THEIR PREPARATION, THEIR USE IN PAPER MANUFACTURING AND PAPER TREATING AGENTS CONTAINING THEM BAYER AG (DE) 1984-08-08 EP disclosed
US-4423194-A IMIDATION OF COPOLYMERS OF MALEIC ANHYDRIDE AND AN OLEFIN WITH AN AMINE BAYER AKTIENGESELLSCHAFT (DE) 1983-12-27 US disclosed