Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 11/20 | 0.55 |
| ▸ | TOP2B | Q02880 | 11/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | ALB | P02768 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TUBB | P07437 | 1/20 | 0.49 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.49 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.49 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.49 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.49 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.49 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.49 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11053850 | 0.88 | TOP2A (0.43) | TOP2ATOP2BLMNAKDM4EALDH1A1 | |
| SCHEMBL9461537 | 0.80 | KDM4E (0.69) | TOP2ALMNAKDM4EALDH1A1HPGD | |
| SCHEMBL9461021 | 0.77 | KDM4E (0.65) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10943767 | 0.76 | KDM4E (0.43) | TOP2ATOP2BLMNAKDM4EALDH1A1 | |
| SCHEMBL10945685 | 0.76 | KDM4E (0.63) | TOP2ATOP2BLMNAKDM4EALDH1A1 | |
| SCHEMBL9871406 | 0.75 | KDM4E (0.44) | TOP2ATOP2BLMNAKDM4EALDH1A1 | |
| SCHEMBL10744176 | 0.72 | TOP2A (0.61) | TOP2ATOP2BLMNAKDM4EALDH1A1 | |
| SCHEMBL11183972 | 0.71 | LMNA (0.72) | TOP2ATOP2BLMNAKDM4EALDH1A1 | |
| SCHEMBL9036040 | 0.71 | LMNA (0.61) | TOP2ATOP2BLMNAKDM4EALDH1A1 | |
| SCHEMBL9582225 | 0.71 | LMNA (0.61) | TOP2ATOP2BLMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443447-A | Phenyl-substituted tricyclic antibacterial agents | RIKER LABORATORIES, INC. (US) | 1984-04-17 | — | — | US | disclosed |