Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9873589 | 0.85 | KDM4E (0.62) | KDM4EKMT2AALDH1A1POLBGSK3B | |
| SCHEMBL9873617 | 0.78 | KDM4E (0.53) | KDM4EKMT2AALDH1A1POLBGSK3B | |
| SCHEMBL9873918 | 0.75 | GSK3B (0.38) | KDM4EKMT2AALDH1A1POLBLMNA | |
| SCHEMBL9873914 | 0.75 | GSK3B (0.38) | KDM4EKMT2AALDH1A1POLBLMNA | |
| SCHEMBL11050375 | 0.75 | TOP2A (0.55) | KDM4EKMT2AALDH1A1POLBLMNA | |
| SCHEMBL9872702 | 0.74 | GSK3B (0.52) | KDM4EKMT2AALDH1A1POLBGSK3B | |
| SCHEMBL9872703 | 0.73 | CNR1 (0.45) | KDM4EKMT2ATUBB4ATUBBTUBA3C | |
| SCHEMBL9874750 | 0.73 | CNR1 (0.45) | KDM4EKMT2ATUBB4ATUBBTUBA3C | |
| SCHEMBL9875270 | 0.72 | GSK3B (0.50) | KDM4EKMT2AALDH1A1POLBGSK3B | |
| SCHEMBL9873482 | 0.71 | GSK3B (0.52) | KDM4EKMT2AGSK3BTOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990508-A | Reduced side effects | TOYAMA CHEMICAL CO., LTD. (JP) | 1991-02-05 | — | — | US | disclosed |