SCHEMBL11050442

SCHEMBL11050442

CCCCCCCCc1ccccc1Cc1ccc2cccnc2c1O

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.46
TRPV1 Q8NER1 1/20 0.43
RAB9A P51151 4/20 0.43
HSP90AA1 P07900 4/20 0.43
NPC1 O15118 3/20 0.43
PAX8 Q06710 2/20 0.43
KMT2A Q03164 2/20 0.43
LIPG Q9Y5X9 1/20 0.41
SAE1 Q9UBE0 1/20 0.41
UBA2 Q9UBT2 1/20 0.41
KDM4E B2RXH2 1/20 0.40
MAPK1 P28482 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
TYR P14679 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.39
EGLN1 Q9GZT9 3/20 0.39
ALDH1A1 P00352 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11049726 1.00 BCHE (0.46) BCHETRPV1RAB9AHSP90AA1NPC1
SCHEMBL11057993 1.00 BCHE (0.46) BCHETRPV1RAB9AHSP90AA1NPC1
SCHEMBL9397782 0.90 TYR (0.49) BCHETRPV1RAB9AHSP90AA1NPC1
SCHEMBL11759262 0.90 TYR (0.49) BCHETRPV1RAB9AHSP90AA1NPC1
SCHEMBL11757253 0.90 TYR (0.49) BCHETRPV1RAB9AHSP90AA1NPC1
SCHEMBL10824010 0.90 TYR (0.49) BCHETRPV1RAB9AHSP90AA1NPC1
SCHEMBL11786290 0.90 TYR (0.49) BCHETRPV1RAB9AHSP90AA1NPC1
SCHEMBL8937738 0.90 TYR (0.49) BCHETRPV1RAB9AHSP90AA1NPC1
SCHEMBL10705017 0.88 TRPV1 (0.49) BCHETRPV1RAB9AHSP90AA1NPC1
SCHEMBL11696829 0.82 TRPV1 (0.43) BCHETRPV1RAB9AHSP90AA1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4437994-A Extraction of metal ions from aqueous solution THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE INTERIOR (US) 1984-03-20 US disclosed
US-4042664-A HALOGENATION, SOLVENT EXTRACTION DEEPSEA VENTURES, INC. (US) 1977-08-16 US disclosed
US-4012483-A Separation of cobalt from nickel in ammoniacal solutions using 8-hydroxyquinolines DEEPSEA VENTURES, INC. (US) 1977-03-15 US disclosed
US-3984520-A ION EXCHANGING DEEPSEA VENTURES, INC. (US) 1976-10-05 US disclosed
US-3950486-A REACTION WITH HYDROGEN HALIDE DEEPSEA VENTURES, INC. (US) 1976-04-13 US disclosed
US-3930974-A TWO STAGE SELECTIVE LEACHING OF METAL VALUES FROM OCEAN FLOOR NODULE ORE DEEPSEA VENTURES, INC. (US) 1976-01-06 US disclosed