Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8937738 | 0.98 | TYR (0.49) | TRPV1TYRBCHEHSP90AA1RAB9A | |
| SCHEMBL11759262 | 0.98 | TYR (0.49) | TRPV1TYRBCHEHSP90AA1RAB9A | |
| SCHEMBL9397782 | 0.98 | TYR (0.49) | TRPV1TYRBCHEHSP90AA1RAB9A | |
| SCHEMBL11786290 | 0.98 | TYR (0.49) | TRPV1TYRBCHEHSP90AA1RAB9A | |
| SCHEMBL10824010 | 0.98 | TYR (0.49) | TRPV1TYRBCHEHSP90AA1RAB9A | |
| SCHEMBL11757253 | 0.98 | TYR (0.49) | TRPV1TYRBCHEHSP90AA1RAB9A | |
| SCHEMBL1714944 | 0.89 | BCHE (0.49) | BCHEHSP90AA1RAB9ANPC1PAX8 | |
| SCHEMBL11050442 | 0.88 | BCHE (0.46) | TRPV1TYRBCHEHSP90AA1RAB9A | |
| SCHEMBL11057993 | 0.88 | BCHE (0.46) | TRPV1TYRBCHEHSP90AA1RAB9A | |
| SCHEMBL11049726 | 0.88 | BCHE (0.46) | TRPV1TYRBCHEHSP90AA1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150025237-A1 | Methods and Compounds Useful in the Synthesis of Orexin-2 Receptor Antagonists | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2015-01-22 | — | — | US | claimed |
| EP-2814798-A1 | METHODS AND COMPOUNDS USEFUL IN THE SYNTHESIS OF OREXIN-2 RECEPTOR ANTAGONISTS | Eisai R&D Management Co., Ltd. (JP) | 2014-12-24 | — | — | EP | claimed |
| WO-2013123240-A1 | METHODS AND COMPOUNDS USEFUL IN THE SYNTHESIS OF OREXIN-2 RECEPTOR ANTAGONISTS | EISAI R&D MANAGEMENT CO., LTD (JP) | 2013-08-22 | — | — | WO | claimed |
| EP-3847889-A1 | BIOCIDAL COMPOSITIONS COMPRISING IRON CHELATORS | Arch Chemicals, Inc. (US) | 2021-07-14 | — | — | EP | disclosed |
| US-20200170249-A1 | Biocidal Compositions Comprising Iron Chelators | ARCH CHEMICALS, INC. | 2020-06-04 | — | — | US | disclosed |
| US-10433548-B2 | Biocidal compositions comprising iron chelators | ARCH CHEMICALS, INC. (US) | 2019-10-08 | — | — | US | disclosed |
| EP-2906038-A1 | BIOCIDAL COMPOSITIONS COMPRISING IRON CHELATORS | Arch Chemicals, Inc. (US) | 2015-08-19 | — | — | EP | disclosed |
| CN-104780760-A | Antimicrobial compositions comprising iron chelators | ARCH CHEM INC | 2015-07-15 | — | — | CN | disclosed |
| US-20140154189-A1 | Biocidal Compositions Comprising Iron Chelators | ARCH CHEMICALS, INC. (US) | 2014-06-05 | — | — | US | disclosed |
| US-4738796-A | HEAT STABILIZATION USING MIXTURE OF 8-HYDROXYQUINOLINE AND ORGANIC PHOSPHATES | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1988-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10433548-B2 | Biocidal compositions comprising iron chelators | SLC40A1, TFRC, SLC39A14 | TRPV1 1194/4885TYR 408/4885BCHE 1279/4885 |
| US-20150025237-A1 | Methods and Compounds Useful in the Synthesis of Orexin-2 Receptor Antagonists | HCRTR2, HCRTR1, NPY2R | TRPV1 287/4885TYR 1074/4885BCHE 1047/4885 |
| US-20140154189-A1 | Biocidal Compositions Comprising Iron Chelators | SLC40A1, TFRC, SLC39A14 | TRPV1 1194/4885TYR 408/4885BCHE 1279/4885 |
| US-20200170249-A1 | Biocidal Compositions Comprising Iron Chelators | SLC40A1, TFRC, SLC39A14 | TRPV1 1194/4885TYR 408/4885BCHE 1279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.