SCHEMBL8937738

SCHEMBL8937738

CCCCCCCCCCCCc1ccc2cccnc2c1O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 2/20 0.49
TRPV1 Q8NER1 1/20 0.48
BCHE P06276 1/20 0.45
HSP90AA1 P07900 5/20 0.45
RAB9A P51151 3/20 0.45
KMT2A Q03164 2/20 0.45
NPC1 O15118 2/20 0.45
PAX8 Q06710 2/20 0.45
ALDH1A1 P00352 1/20 0.44
EGLN1 Q9GZT9 2/20 0.43
ALOX5 P09917 2/20 0.43
PTGS2 P35354 1/20 0.43
TDP1 Q9NUW8 3/20 0.43
TSHR P16473 3/20 0.43
TP53 P04637 2/20 0.43
CYP3A4 P08684 2/20 0.43
MAPT P10636 2/20 0.43
ALOX15 P16050 2/20 0.43
HTT P42858 2/20 0.43
KDM4E B2RXH2 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11786290 1.00 TYR (0.49) TYRTRPV1BCHEHSP90AA1RAB9A
SCHEMBL9397782 1.00 TYR (0.49) TYRTRPV1BCHEHSP90AA1RAB9A
SCHEMBL10824010 1.00 TYR (0.49) TYRTRPV1BCHEHSP90AA1RAB9A
SCHEMBL11759262 1.00 TYR (0.49) TYRTRPV1BCHEHSP90AA1RAB9A
SCHEMBL11757253 1.00 TYR (0.49) TYRTRPV1BCHEHSP90AA1RAB9A
SCHEMBL10705017 0.98 TRPV1 (0.49) TYRTRPV1BCHEHSP90AA1RAB9A
SCHEMBL11049726 0.90 BCHE (0.46) TYRTRPV1BCHEHSP90AA1RAB9A
SCHEMBL11057993 0.90 BCHE (0.46) TYRTRPV1BCHEHSP90AA1RAB9A
SCHEMBL11050442 0.90 BCHE (0.46) TYRTRPV1BCHEHSP90AA1RAB9A
SCHEMBL1714944 0.88 BCHE (0.49) BCHEHSP90AA1RAB9AKMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4818504-A SOLVENT EXTRACTION WITH WATER-INSOLUBLE SUBSTITUTED 8-HYDROXY QUINOLINE RHONE-POULENC CHIMIE (FR) 1989-04-04 US claimed
CN-1049238-C Copper-containing organometallic complexes and concontrates and diesel fuels containing same LUBRICOL CO (US) 2000-02-09 CN disclosed
CN-1039721-C Organometallic complex-antioxidant combinations, concentrates and diesel fuels containing same LUBRIZOL CORP (US) 1998-09-09 CN disclosed
US-5562742-A USED TO LOWER THE IGNITION TEMPERATURE OF EXHAUST PARTICLES COLLECTED IN THE TRAP THE LUBRIZOL CORPORATION (US) 1996-10-08 US disclosed
US-5534039-A POLLUTION CONTROL FOR DIESEL ENGINES THE LUBRIZOL CORPORATION (US) 1996-07-09 US disclosed
EP-0539576-B1 ORGANOMETALLIC COMPLEX-ANTIOXIDANT COMBINATIONS, AND CONCENTRATES AND DIESEL FUELS CONTAINING SAME LUBRIZOL CORP (US) 1996-05-29 EP disclosed
US-5518510-A EXHAUST SYSTEMS WITH TRAPS FOR DIESEL ENGINES THE LUBRIZOL CORPORATION (US) 1996-05-21 US disclosed
EP-0539578-B1 COPPER-CONTAINING ORGANOMETALLIC COMPLEXES AND CONCENTRATES AND DIESEL FUELS CONTAINING SAME LUBRIZOL CORP (US) 1996-02-28 EP disclosed
US-5376154-A For diesel engines equipped with an exhaust system particulate trap; lowers ignition temperature of those particles THE LUBRIZOL CORPORATION (US) 1994-12-27 US disclosed
US-5360459-A Fuel additives THE LUBRIZOL CORPORATION (US) 1994-11-01 US disclosed
CN-1066677-A Cupric organometallic complex and the enriched material and the diesel oil fuel that contain this title complex LUBRIZOL CORP (US) 1992-12-02 CN disclosed
WO-1992020765-A1 DIESEL FUELS CONTAINING ORGANOMETALLIC COMPLEXES THE LUBRIZOL CORPORATION (US) 1992-11-26 WO disclosed
WO-1992020764-A1 COPPER-CONTAINING ORGANOMETALLIC COMPLEXES AND CONCENTRATES AND DIESEL FUELS CONTAINING SAME THE LUBRIZOL CORPORATION (US) 1992-11-26 WO disclosed
WO-1992020762-A1 ORGANOMETALLIC COMPLEX-ANTIOXIDANT COMBINATIONS, AND CONCENTRATES AND DIESEL FUELS CONTAINING SAME THE LUBRIZOL CORPORATION (US) 1992-11-26 WO disclosed
WO-1992020763-A1 LOW-SULFUR DIESEL FUELS CONTAINING ORGANOMETALLIC COMPLEXES THE LUBRIZOL CORPORATION (US) 1992-11-26 WO disclosed
US-5071989-A Ionophores DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1991-12-10 US disclosed
US-4065455-A REAGENTS FOR ION EXCHANGE EXTRACTION OF METALS GENERAL MILLS CHEMICALS, INC. (US) 1977-12-27 US disclosed
US-4051223-A SELECTIVE, CALCIUM SEPARATION, HYDROGEN ION EXCHANGE RESIN GENERAL MILLS CHEMICALS, INC. (US) 1977-09-27 US disclosed
US-4009116-A Process of preparing substantially organic waste liquids containing radioactive or toxic substances for safe, non-pollutive handling, transportation and permanent storage BAYER AKTIENGESELLSCHAFT (DT) 1977-02-22 US disclosed
US-3960762-A Production of absorbents BAYER AKTIENGESELLSCHAFT (DT) 1976-06-01 US disclosed