Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CCR2 | P41597 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KLK7 | P49862 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3468425 | 0.98 | TDP1 (0.46) | TDP1CA1CA2CCR2HPGD | |
| Hydrochloric Acid SCHEMBL11049903 | 0.95 | TDP1 (0.43) | TDP1CA1CA2CCR2HPGD | |
| Pyridine SCHEMBL18007665 | 0.83 | CA1 (0.39) | TDP1CA1CA2CCR2HPGD | |
| SCHEMBL13826361 | 0.80 | CA1 (0.46) | TDP1CA1CA2TSHRALDH1A1 | |
| SCHEMBL10274786 | 0.76 | CCR2 (0.50) | TDP1CCR2ALDH1A1L3MBTL1MAPT | |
| SCHEMBL214431 | 0.74 | TDP1 (0.46) | TDP1CCR2HPGDALDH1A1L3MBTL1 | |
| SCHEMBL12880157 | 0.74 | ALDH1A1 (0.37) | CA1CA2TSHRALDH1A1PKM | |
| Cimlanod SCHEMBL15878610 | 0.74 | CA1 (0.45) | TDP1CA1CA2CCR2ALDH1A1 | |
| SCHEMBL11050566 | 0.73 | TDP1 (0.43) | TDP1CCR2ALDH1A1L3MBTL1MAPT | |
| SCHEMBL17208243 | 0.71 | CA1 (0.38) | CA1CA2TSHRALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4430355-A | ARTIFICIAL SWEETENER | DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1984-02-07 | — | — | US | disclosed |
| US-4233333-A | 4,5-Dimethyl-thieno[3,2-d]isothiazolo-3(2H)-one-1,1-dioxides, compositions, and methods of use as a sweetener | BOEHRINGER INGELHEIM GMBH (DE) | 1980-11-11 | — | — | US | disclosed |