Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 4/20 | 0.50 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | PDE6D | O43924 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17621 | 0.85 | HSD17B10 (0.62) | BRD4LIMK2HSD17B10ESR1PDE6D | |
| Hydrochloric Acid SCHEMBL233781 | 0.83 | HSD17B10 (0.60) | BRD4LIMK2HSD17B10ESR1PDE6D | |
| Bromide SCHEMBL811908 | 0.83 | HSD17B10 (0.60) | BRD4LIMK2HSD17B10ESR1PDE6D | |
| Fluoride SCHEMBL10339918 | 0.83 | HSD17B10 (0.60) | BRD4LIMK2HSD17B10ESR1PDE6D | |
| Iodide SCHEMBL28519464 | 0.83 | HSD17B10 (0.60) | BRD4LIMK2HSD17B10ESR1PDE6D | |
| Fluoride SCHEMBL10906966 | 0.82 | LIMK2 (0.59) | BRD4LIMK2HSD17B10ESR1PDE6D | |
| Bromide SCHEMBL811907 | 0.82 | LIMK2 (0.59) | BRD4LIMK2HSD17B10ESR1PDE6D | |
| Fluoride Ion SCHEMBL10906965 | 0.82 | LIMK2 (0.59) | BRD4LIMK2HSD17B10ESR1PDE6D | |
| SCHEMBL5981532 | 0.82 | LIMK2 (0.63) | BRD4LIMK2HSD17B10ESR1PDE6D | |
| SCHEMBL10906967 | 0.79 | LIMK2 (0.56) | CA1CA2BRD4LIMK2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4430445-A | POLYAMIDINE HOHO- AND COPOLYMERS; OXIDATION RESISTANCE; METAL EXTRACTION; POLYEPOXIDE CURING AGENTS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1984-02-07 | — | — | US | disclosed |