Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.60 |
| ▸ | BRD4 | O60885 | 3/20 | 0.58 |
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | PDE6D | O43924 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17621 | 0.98 | HSD17B10 (0.62) | HSD17B10LIMK2BRD4ESR1PDE6D | |
| Iodide SCHEMBL28519464 | 0.96 | HSD17B10 (0.60) | HSD17B10LIMK2BRD4ESR1PDE6D | |
| Fluoride SCHEMBL10339918 | 0.96 | HSD17B10 (0.60) | HSD17B10LIMK2BRD4ESR1PDE6D | |
| Hydrochloric Acid SCHEMBL233781 | 0.96 | HSD17B10 (0.60) | HSD17B10LIMK2BRD4ESR1PDE6D | |
| Fluoride Ion SCHEMBL10906965 | 0.95 | LIMK2 (0.59) | HSD17B10LIMK2BRD4ESR1PDE6D | |
| SCHEMBL5981532 | 0.95 | LIMK2 (0.63) | HSD17B10LIMK2BRD4ESR1PDE6D | |
| Fluoride SCHEMBL10906966 | 0.95 | LIMK2 (0.59) | HSD17B10LIMK2BRD4ESR1PDE6D | |
| Bromide SCHEMBL811907 | 0.95 | LIMK2 (0.59) | HSD17B10LIMK2BRD4ESR1PDE6D | |
| SCHEMBL10906967 | 0.92 | LIMK2 (0.56) | HSD17B10LIMK2BRD4ESR1PDE6D | |
| SCHEMBL2840217 | 0.90 | LIMK2 (0.58) | HSD17B10LIMK2BRD4ESR1PDE6D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119307169-A | Curable composition, cured product, overcoat film for flexible wiring board, and method for producing flexible wiring board | 日保丽公司 | 2025-01-14 | — | — | CN | disclosed |
| EP-3395848-B1 | POLYURETHANE, CURABLE COMPOSITION, OVERCOAT FILM, AND FLEXIBLE WIRING BOARD AND PRODUCTION METHOD THEREFORE | NIPPON POLYTECH CORP (JP) | 2024-02-28 | — | — | EP | disclosed |
| EP-2977406-B1 | CURABLE COMPOSITION | LG CHEMICAL LTD (KR) | 2024-01-24 | — | — | EP | disclosed |
| CN-114080408-B | Cured product, overcoat film, and flexible wiring board | 日保丽公司 | 2023-08-25 | — | — | CN | disclosed |
| CN-114096579-B | Polyurethane and curable composition | 日保丽公司 | 2023-06-09 | — | — | CN | disclosed |
| CN-114096579-A | Polyurethane and curable composition | 日保丽公司 | 2022-02-25 | — | — | CN | disclosed |
| CN-114080408-A | Cured product, overcoat film, and flexible wiring board | 日保丽公司 | 2022-02-22 | — | — | CN | disclosed |
| CN-114072444-A | Curable composition, cured product, overcoat film, flexible wiring board, and method for producing same | 日保丽公司 | 2022-02-18 | — | — | CN | disclosed |
| CN-109071954-B | Curable composition, cured film using same, and overcoat film | 日保丽公司 | 2021-11-02 | — | — | CN | disclosed |
| CN-109071955-B | Curable composition, cured film using same, and overcoat film | 日保丽公司 | 2021-10-15 | — | — | CN | disclosed |
| CN-102272186-A | (Poly)carbonate polyol and carboxyl group-containing polyurethane using the (poly)carbonate polyol as starting material | — | 2011-12-07 | — | — | CN | disclosed |
| CN-102272185-A | Carboxyl group-containing polyurethane | — | 2011-12-07 | — | — | CN | disclosed |
| EP-2390276-A1 | CARBOXYL GROUP-CONTAINING POLYURETHANE | Showa Denko K.K. (JP) | 2011-11-30 | — | — | EP | disclosed |
| EP-2390277-A1 | (POLY)CARBONATE POLYOL AND CARBOXYL GROUP-CONTAINING POLYURETHANE USING THE (POLY)CARBONATE POLYOL AS STARTING MATERIAL | Showa Denko K.K. (JP) | 2011-11-30 | — | — | EP | disclosed |
| CN-102264838-A | Curable composition | — | 2011-11-30 | — | — | CN | disclosed |
| US-20110272182-A1 | CARBOXYL GROUP-CONTAINING POLYURETHANE | SHOWA DENKO K.K. (JP) | 2011-11-10 | — | — | US | disclosed |
| US-20110272183-A1 | (POLY)CARBONATE POLYOL AND CARBOXYL GROUP-CONTAINING POLYURETHANE OBTAINED FROM THE (POLY)CARBONATE POLYOL | SHOWA DENKO K.K. (JP) | 2011-11-10 | — | — | US | disclosed |
| EP-2383310-A1 | CURABLE COMPOSITION | Showa Denko K.K. (JP) | 2011-11-02 | — | — | EP | disclosed |
| US-20110257257-A1 | COMPOSITION FOR TREATMENT OF EPITHELIAL TISSUE | NOVODERMIX INTERNATIONAL LIMITED (VG) | 2011-10-20 | — | — | US | disclosed |
| US-20110253426-A1 | CURABLE COMPOSITION | SHOWA DENKO K.K. (JP) | 2011-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110272183-A1 | (POLY)CARBONATE POLYOL AND CARBOXYL GROUP-CONTAINING POLYURETHANE OBTAINED FROM THE (POLY)CARBONATE POLYOL | PUF60, PARG, PIK3C2G | HSD17B10 895/4885LIMK2 230/4885BRD4 2656/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.