Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MLYCD | O95822 | 1/20 | 0.54 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.50 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.49 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.49 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19707227 | 0.91 | TSHR (0.70) | TSHRRAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL17460946 | 0.91 | HTT (0.62) | RAB9ASMN1; SMN2NPC1ALDH1A1PKM | |
| SCHEMBL2512409 | 0.88 | MLYCD (0.65) | TSHRRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL28437707 | 0.85 | TSHR (0.62) | TSHRRAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL28437969 | 0.85 | RAB9A (0.57) | RAB9ASMN1; SMN2NPC1MAPTALDH1A1 | |
| SCHEMBL16518678 | 0.84 | MLYCD (0.69) | TSHRRAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL28429264 | 0.84 | TSHR (0.60) | TSHRRAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL9871496 | 0.83 | RAB9A (0.63) | TSHRRAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL18010562 | 0.83 | MEN1 (0.55) | TSHRRAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL28429878 | 0.83 | MEN1 (0.60) | TSHRRAB9ASMN1; SMN2NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4444863-A | UREA COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1984-04-24 | — | — | US | disclosed |