SCHEMBL1105115

SCHEMBL1105115

CCCC(CC)C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18638510 1.00
SCHEMBL18077921 1.00
SCHEMBL12059211 0.88 TSHR (0.30)
SCHEMBL12651612 0.83 FDPS (0.38)
SCHEMBL28320496 0.81 FDPS (0.41)
Hydrochloric Acid SCHEMBL9052786 0.81 FDPS (0.36)
SCHEMBL83145 0.81
SCHEMBL23902176 0.80 TRPM8 (0.31)
SCHEMBL22294036 0.80
SCHEMBL8160399 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2794719-B1 METHODS FOR POLYMER SYNTHESIS SAUDI ARAMCO TECH CO (SA) 2023-08-23 EP disclosed
WO-2023001069-A1 MACROCYCLIC AMIDE COMPOUNDS AND APPLICATION THEREOF 南京明德新药研发有限公司 2023-01-26 WO disclosed
US-20220218709-A1 TOLL LIKE RECEPTOR MODULATOR COMPOUNDS GILEAD SCIENCES, INC. 2022-07-14 US disclosed
EP-3630771-B1 5,6-FUSED-BICYCLIC COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PARASITIC DISEASES NOVARTIS AG (CH) 2022-06-29 EP disclosed
US-11344546-B2 Benzamide compounds Recurium IP Holding, LLC (US) 2022-05-31 US disclosed
US-20220162246-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-05-26 US disclosed
EP-3936192-A1 PYRROLOPYRAZOLE DERIVATIVE Daiichi Sankyo Company, Limited (JP) 2022-01-12 EP disclosed
US-20210009543-A1 BENZAMIDE COMPOUNDS ZENO MANAGEMENT, INC. 2021-01-14 US disclosed
EP-3019480-B1 2,4- OR 4,6-DIAMINOPYRIMIDINE COMPOUNDS AS IDH2 MUTANTS INHIBITORS FOR THE TREATMENT OF CANCER AGIOS PHARMACEUTICALS INC (US) 2020-05-06 EP disclosed
CN-110431142-A Alicyclic substituted pyrazolo [1,5-a] pyrimidine derivatives of pharmacological activity RICHTER GEDEON NYRT 2019-11-08 CN disclosed
CN-101384581-B Benzoyl-piperidine derivatives as 5HT2/D3 modulators HOFFMANN LA ROCHE 2013-09-18 CN disclosed
US-8153248-B2 Plastic lens and method of producing plastic lens SEIKO EPSON CORPORATION (JP) 2012-04-10 US disclosed
US-7854508-B2 includes plastic lens base material, hard coat layer formed on lens, organic antireflection film formed on hard coat layer, and a primer layer between plastic lens base material and hard coat layer; lens base material contains sulfur atom, hard coat layer contains fine metal oxide, organosilicon compound SEIKO EPSON CORPORATION (JP) 2010-12-21 US disclosed
US-20090181959-A1 HETEROARYL SUBSTITUTED PYRROLO[2,3-b]PYRIDINES AND PYRROLO[2,3-b]PYRIMIDINES AS JANUS KINASE INHIBITORS INCYTE CORPORATION (US) 2009-07-16 US disclosed
CN-101415688-A Quinazolone derivative with B-RAF inhibition activity ASTRAZENECA AB (SE) 2009-04-22 CN disclosed
CN-101384581-A Benzoyl-piperidine derivatives as 5HT2/D3 modulators HOFFMANN LA ROCHE (CH) 2009-03-11 CN disclosed
US-20090040457-A1 PLASTIC LENS AND MANUFACTURING METHOD OF PLASTIC LENS SEIKO EPSON CORPORATION (JP) 2009-02-12 US disclosed
US-7374812-B2 Low refractive index coating composition for use in antireflection polymer film coatings and manufacturing method 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-05-20 US disclosed
EP-0406748-B1 Dehydrofluorination and dehydrogenation of fluorinated alkanes ATOCHEM NORTH AMERICA (US) 1994-09-28 EP disclosed
EP-0406748-A2 Dehydrofluorination and dehydrogenation of fluorinated alkanes ATOCHEM NORTH AMERICA, INC. (US) 1991-01-09 EP disclosed