Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2905084 | 0.80 | MAPT (0.57) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL2905085 | 0.80 | MAPT (0.57) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL11051174 | 0.73 | MAPT (0.50) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL31545915 | 0.72 | MAPT (0.55) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL2897385 | 0.72 | MAPT (0.55) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL11051178 | 0.72 | MMP1 (0.43) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL2900787 | 0.69 | MAPT (0.53) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL2900788 | 0.69 | MAPT (0.53) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| 2-Nitroaniline SCHEMBL22394595 | 0.68 | MAPK1 (0.51) | MAPTALDH1A1MEN1KMT2APDE7A | |
| SCHEMBL7359553 | 0.67 | GAA (0.46) | MAPTKDM4EKMT2AGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4483794-A | UROGENITAL MUSCLE RELAXANT | CESKOSLOVENSKA AKADEMIE VED (CS) | 1984-11-20 | — | — | US | disclosed |