Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8886828 | 0.72 | MMP2 (0.36) | MMP2MAPTKMT2AGAASMN1; SMN2 | |
| SCHEMBL11051183 | 0.72 | MAPT (0.46) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL10864271 | 0.71 | ALDH1A1 (0.50) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL10373336 | 0.71 | ALDH1A1 (0.50) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL27630263 | 0.71 | GPR35 (0.45) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL11797633 | 0.70 | ALDH1A1 (0.49) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL9543128 | 0.68 | ALDH1A1 (0.42) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL11051174 | 0.68 | MAPT (0.50) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL3427046 | 0.66 | ALDH1A1 (0.52) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL2905084 | 0.66 | MAPT (0.57) | MMP1MMP2MMP9MMP8MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4483794-A | UROGENITAL MUSCLE RELAXANT | CESKOSLOVENSKA AKADEMIE VED (CS) | 1984-11-20 | — | — | US | disclosed |