Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.41 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22246044 | 0.84 | KDM4E (0.42) | KDM4ECISD1SLC16A3ALDH1A1CYP3A4 | |
| SCHEMBL15440 | 0.84 | KDM4E (0.42) | KDM4ECISD1SLC16A3ALDH1A1CYP3A4 | |
| SCHEMBL15441 | 0.84 | KDM4E (0.42) | KDM4ECISD1SLC16A3ALDH1A1CYP3A4 | |
| SCHEMBL541123 | 0.80 | KDM4E (0.40) | KDM4ECISD1SLC16A3ALDH1A1CYP3A4 | |
| SCHEMBL13696929 | 0.78 | KDM4E (0.39) | KDM4ECISD1SLC16A3ALDH1A1CYP3A4 | |
| SCHEMBL2402354 | 0.78 | KDM4E (0.36) | KDM4ECISD1SLC16A3ALDH1A1CYP3A4 | |
| SCHEMBL448846 | 0.78 | KDM4E (0.39) | KDM4ECISD1SLC16A3ALDH1A1CYP3A4 | |
| SCHEMBL7552150 | 0.77 | KDM4E (0.38) | KDM4ECISD1SLC16A3ALDH1A1CYP3A4 | |
| SCHEMBL2404080 | 0.77 | KDM4E (0.39) | KDM4ECISD1SLC16A3ALDH1A1CYP3A4 | |
| Lactic Acid SCHEMBL29113122 | 0.77 | TP53 (0.44) | KDM4ECISD1SLC16A3ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4431790-A | REACTION PRODUCT OF POLYOXYALKYLENEPOLYAMINE, HYDROXY-ACRYLIC DERIVATIVE, EPOXIDE | TEXACO INC. (US) | 1984-02-14 | — | — | US | disclosed |