Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.40 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15440 | 0.82 | KDM4E (0.42) | KDM4ECISD1SLC16A3ALDH1A1CYP3A4 | |
| SCHEMBL22246044 | 0.82 | KDM4E (0.42) | KDM4ECISD1SLC16A3ALDH1A1CYP3A4 | |
| SCHEMBL15441 | 0.82 | KDM4E (0.42) | KDM4ECISD1SLC16A3ALDH1A1CYP3A4 | |
| SCHEMBL11051248 | 0.80 | KDM4E (0.41) | KDM4ECISD1SLC16A3ALDH1A1CYP3A4 | |
| SCHEMBL448846 | 0.77 | KDM4E (0.39) | KDM4ECISD1SLC16A3ALDH1A1CYP3A4 | |
| SCHEMBL13696929 | 0.77 | KDM4E (0.39) | KDM4ECISD1SLC16A3ALDH1A1CYP3A4 | |
| SCHEMBL21234916 | 0.76 | ALDH1A1 (0.48) | KDM4EALDH1A1HPGDLMNAKMT2A | |
| SCHEMBL7552150 | 0.75 | KDM4E (0.38) | KDM4ECISD1SLC16A3ALDH1A1CYP3A4 | |
| SCHEMBL2404080 | 0.75 | KDM4E (0.39) | KDM4ECISD1SLC16A3ALDH1A1CYP3A4 | |
| SCHEMBL2231637 | 0.75 | KDM4E (0.39) | KDM4ECISD1SLC16A3ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153743-B2 | Controlled exotherm of cyanoacrylate formulations | CLOSURE MEDICAL CORPORATION (US) | 2012-04-10 | — | — | US | disclosed |
| EP-2413943-A1 | CONTROLLED EXOTHERM OF CYANOACRYLATE FORMULATIONS | Ethicon, Inc (US) | 2012-02-08 | — | — | EP | disclosed |
| EP-2307515-A2 | CONTROLLED EXOTHERM OF CYANOACRYLATE FORMULATIONS | Ethicon, Inc. (US) | 2011-04-13 | — | — | EP | disclosed |
| WO-2010114779-A1 | CONTROLLED EXOTHERM OF CYANOACRYLATE FORMULATIONS | ETHICON, INC. (US) | 2010-10-07 | — | — | WO | disclosed |
| US-20100249698-A1 | CONTROLLED EXOTHERM OF CYANOACRYLATE FORMULATIONS | ETHICON, INC. | 2010-09-30 | — | — | US | disclosed |
| US-20100030258-A1 | Controlled Exotherm of Cyanoacrylate Formulations | ETHICON, INC. | 2010-02-04 | — | — | US | disclosed |
| WO-2010014641-A2 | CONTROLLED EXOTHERM OF CYANOACRYLATE FORMULATIONS | CLOSURE MEDICAL CORPORATION (US) | 2010-02-04 | — | — | WO | disclosed |