Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 9/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid Methyl Ester SCHEMBL11879995 | 0.80 | HCAR2 (0.39) | TSHRALDH1A1HPGDKEAP1NFE2L2 | |
| Acrylic Acid Methyl Ester SCHEMBL6408257 | 0.80 | TDP1 (0.48) | TSHRALDH1A1HPGDKEAP1NFE2L2 | |
| Acrylic Acid SCHEMBL3834308 | 0.80 | LMNA (0.43) | TSHRALDH1A1TP53HSD17B10 | |
| SCHEMBL3629361 | 0.78 | TSHR (0.69) | TSHRALDH1A1HPGDHCAR2TP53 | |
| SCHEMBL28278907 | 0.78 | ALDH1A1 (0.33) | TSHRALDH1A1 | |
| Acrylic Acid Methyl Ester SCHEMBL27620192 | 0.78 | — | — | |
| Acrylic Acid Methyl Ester SCHEMBL27839206 | 0.78 | — | — | |
| Acrylic Acid Methyl Ester SCHEMBL18065078 | 0.77 | — | — | |
| Acrylic Acid Methyl Ester SCHEMBL8910822 | 0.77 | TSHR (0.48) | TSHRALDH1A1HPGDKEAP1NFE2L2 | |
| Acrylic Acid Methyl Ester SCHEMBL28158899 | 0.77 | HCAR2 (0.53) | TSHRALDH1A1HPGDKEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4439201-A | Process for retanning leather with acrylic-based oligomers | CIBA-GEIGY CORPORATION (US) | 1984-03-27 | — | — | US | disclosed |