Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11052123 | 0.93 | MEN1 (0.32) | MEN1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL11046009 | 0.91 | MEN1 (0.36) | MEN1KMT2AMAPK1NOTUMNPC1 | |
| SCHEMBL11051574 | 0.88 | OPRL1 (0.40) | CHRM2CHRM4CHRM1CHRM3ACE | |
| SCHEMBL11046064 | 0.82 | ACE (0.42) | MAPK1NOTUMACE | |
| SCHEMBL11045822 | 0.80 | MEN1 (0.43) | MEN1KMT2ACHRM2CHRM4CHRM1 | |
| SCHEMBL11044573 | 0.78 | KMT2A (0.45) | KMT2AACEOPRL1 | |
| SCHEMBL11050571 | 0.78 | KMT2A (0.45) | KMT2AACEOPRL1 | |
| SCHEMBL11047878 | 0.78 | KMT2A (0.45) | KMT2AACEOPRL1 | |
| SCHEMBL11047768 | 0.76 | MTNR1A (0.38) | MEN1KMT2AMAPK1NOTUMNPC1 | |
| SCHEMBL11043214 | 0.74 | ACE (0.42) | KMT2AMAPK1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4461896-A | 1-[Acylthio) and (mercapto)-1-oxoalkyl]-1,2,3,4-tetrahydroquinoline-2-carboxylic acids | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1984-07-24 | — | — | US | disclosed |