Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 4/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 10/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11040761 | 0.90 | SLC29A1 (0.42) | SLC29A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11047084 | 0.87 | PDE4A (0.41) | SLC29A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11028181 | 0.87 | SLC29A1 (0.43) | SLC29A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2460092 | 0.86 | SLC29A1 (0.45) | SLC29A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11048512 | 0.86 | SLC29A1 (0.41) | SLC29A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11029471 | 0.85 | SLC29A1 (0.41) | SLC29A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11042970 | 0.85 | ALDH1A1 (0.37) | SLC29A1ALDH1A1POLBHPGDTSHR | |
| SCHEMBL11051400 | 0.85 | PDE4A (0.44) | SLC29A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11044287 | 0.84 | SLC29A1 (0.41) | SLC29A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11029563 | 0.84 | SLC29A1 (0.47) | SLC29A1PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4478833-A | ANTICOAGULANTS | DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1984-10-23 | — | — | US | disclosed |
| EP-0055444-A2 | Trisubstituted pyrimido(5,4-d)pyrimidines, their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1982-07-07 | — | — | EP | disclosed |