Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | TSHR | P16473 | 4/20 | 0.59 |
| ▸ | ESR1 | P03372 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.59 |
| ▸ | KDR | P35968 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.52 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9276196 | 0.91 | TDP1 (0.53) | LMNAALDH1A1TSHRESR1TDP1 | |
| SCHEMBL17798293 | 0.90 | RARB (0.64) | LMNAALDH1A1TSHRESR1TDP1 | |
| SCHEMBL9054152 | 0.90 | RARB (0.64) | LMNAALDH1A1TSHRESR1TDP1 | |
| SCHEMBL17824453 | 0.90 | MAPT (0.53) | LMNAALDH1A1TSHRESR1TDP1 | |
| SCHEMBL1995221 | 0.89 | LMNA (0.75) | LMNAALDH1A1TSHRESR1TDP1 | |
| Terephthalic Acid SCHEMBL28622229 | 0.89 | LMNA (0.75) | LMNAALDH1A1TSHRESR1TDP1 | |
| SCHEMBL17824365 | 0.88 | MAPT (0.54) | LMNAALDH1A1TSHRESR1TDP1 | |
| SCHEMBL22832434 | 0.88 | LMNA (0.79) | LMNAALDH1A1TSHRESR1TDP1 | |
| SCHEMBL22832552 | 0.88 | LMNA (0.79) | LMNAALDH1A1TSHRESR1TDP1 | |
| SCHEMBL1919741 | 0.88 | LMNA (0.79) | LMNAALDH1A1TSHRESR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4430408-A | IN BINDER WITH CARBON BLACK SURFACE TREATMENT | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1984-02-07 | — | — | US | claimed |