SCHEMBL11051963

SCHEMBL11051963

COC(=O)CC(CC(=O)OC)N(C=O)OCc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.48
ABCB1 P08183 2/20 0.45
KCNA5 P22460 3/20 0.41
ALDH1A1 P00352 4/20 0.40
KDM4E B2RXH2 1/20 0.40
LMNA P02545 1/20 0.40
MMP1 P03956 3/20 0.39
MAPK1 P28482 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11058157 0.96 MAOB (0.48) MAOBABCB1KCNA5ALDH1A1KDM4E
SCHEMBL6299671 0.79 ALDH1A1 (0.43) ABCB1ALDH1A1KDM4ELMNA
SCHEMBL6298147 0.79 ALDH1A1 (0.43) ABCB1ALDH1A1KDM4ELMNA
SCHEMBL5267908 0.77 ALOX5 (0.39) ALDH1A1L3MBTL1
SCHEMBL10873777 0.76 SLC1A1 (0.45) ALDH1A1LMNAMAPK1L3MBTL1
SCHEMBL7415908 0.76 EPOR (0.45) ALDH1A1L3MBTL1
SCHEMBL27744904 0.75 ALDH1A1 (0.40) MAOBALDH1A1
SCHEMBL5268183 0.75 ALDH1A1 (0.40) MAOBALDH1A1
SCHEMBL7499940 0.75 MAPK1 (0.39) ABCB1MAPK1
Hydrochloric Acid SCHEMBL8687105 0.75 EPOR (0.44) ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0050799-B1 NEW PROCESSES FOR THE PRODUCTION OF DI-ALKYL ESTERS AND OPTICALLY ACTIVE MONO-ALKYL ESTERS OF 3-AMINOGLUTARIC ACID ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1984-12-19 EP disclosed
US-4452897-A ENZYME HYDROLYSIS OF AMINOGLUTARIC ACID ALKYL ESTERS TAKARA SHUZO CO., LTD. (JP) 1984-06-05 US disclosed