Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | RXRA | P19793 | 2/20 | 0.38 |
| ▸ | RXRB | P28702 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7771341 | 0.83 | AKR1B1 (0.43) | AKR1B1SRCPTGS1MAPTTSHR | |
| SCHEMBL6762399 | 0.80 | AKR1B1 (0.55) | AKR1B1MAPTHPGDTSHRTDP1 | |
| SCHEMBL2442291 | 0.78 | HSD17B10 (0.54) | AKR1B1SMN1; SMN2PTGS1MAPTTSHR | |
| SCHEMBL9580151 | 0.78 | AKR1B1 (0.52) | AKR1B1MAPTHPGDTSHRTDP1 | |
| SCHEMBL458360 | 0.76 | — | — | |
| Water SCHEMBL30372687 | 0.75 | CTBP2 (0.59) | AKR1B1PTGS2PTGS1MAPTHPGD | |
| SCHEMBL6713227 | 0.74 | AKR1B1 (0.39) | AKR1B1PTGS2SMN1; SMN2ALOX15PTGS1 | |
| SCHEMBL22344551 | 0.74 | AKR1B1 (0.42) | AKR1B1PTGS2PTGS1TDP1 | |
| SCHEMBL1441910 | 0.74 | AKR1B1 (0.39) | AKR1B1PTGS2SRCPTGS1MAPT | |
| SCHEMBL22344588 | 0.74 | CXCL8 (0.41) | AKR1B1PTGS2SRCRXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482655-A | SUBSTITUTED SUCCINIC ANHYDRIDE COUPLER | MILLIKEN RESEARCH CORPORATION (US) | 1984-11-13 | — | — | US | disclosed |
| US-4328041-A | TREATED WITH SUBSTITUTED SUCCINIC ANHYDRIDE | MILLIKEN RESEARCH CORPORATION (US) | 1982-05-04 | — | — | US | disclosed |
| US-4122062-A | FILLERS | KENRICH PETROCHEMICALS, INC. (US) | 1978-10-24 | — | — | US | disclosed |
| US-4098758-A | ORGANIC ACIDS, FOR USE IN POLYMER SYSTEMS | KENRICH PETROCHEMICALS, INC. (US) | 1978-07-04 | — | — | US | disclosed |
| US-4096110-A | Filled polyesters containing organic titanate esters | KENRICH PETROCHEMICALS, INC. (US) | 1978-06-20 | — | — | US | disclosed |
| US-4094853-A | Alkoxy titanate salts useful as coupling agents | KENRICH PETROCHEMICALS, INC. (US) | 1978-06-13 | — | — | US | disclosed |
| US-4087402-A | USED FOR TREATMENT OF INORGANIC FILLERS | KENRICH PETROCHEMICALS, INC. (US) | 1978-05-02 | — | — | US | disclosed |