Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.39 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | CXCL8 | P10145 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.33 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7771341 | 0.82 | AKR1B1 (0.43) | AKR1B1BCAT2KDM4ECYP1A2MAPT | |
| SCHEMBL9580151 | 0.80 | AKR1B1 (0.52) | AKR1B1KDM4ECYP1A2MAPTTDP1 | |
| SCHEMBL22344551 | 0.77 | AKR1B1 (0.42) | AKR1B1TDP1CXCL8PTGS2AKR1B10 | |
| SCHEMBL22344518 | 0.77 | AKR1B1 (0.39) | AKR1B1BCAT2KDM4ECYP1A2MAPT | |
| SCHEMBL22344588 | 0.77 | CXCL8 (0.41) | AKR1B1KDM4ECYP1A2MAPTTDP1 | |
| SCHEMBL1441910 | 0.77 | AKR1B1 (0.39) | AKR1B1BCAT2KDM4ECYP1A2MAPT | |
| SCHEMBL27810240 | 0.75 | GABRP (0.44) | KDM4ECYP1A2MAPTTDP1HSD17B10 | |
| SCHEMBL490677 | 0.74 | ALDH1A1 (0.48) | KDM4ECYP1A2MAPTTDP1HSD17B10 | |
| SCHEMBL11051979 | 0.74 | AKR1B1 (0.41) | AKR1B1MAPTTDP1HSD17B10ALOX15 | |
| SCHEMBL6762399 | 0.74 | AKR1B1 (0.55) | AKR1B1KDM4ECYP1A2MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004065411-A2 | PEPTIDES | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2004-08-05 | — | — | WO | claimed |
| US-20040138104-A1 | Peptides | THE GOVERNMENT OF THE UNITED STATES OF AMERICA REPRESENTED BY THE SECRETARY, | 2004-07-15 | — | — | US | claimed |
| WO-2004065411-A2 | PEPTIDES | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2004-08-05 | — | — | WO | disclosed |
| US-20040138104-A1 | Peptides | THE GOVERNMENT OF THE UNITED STATES OF AMERICA REPRESENTED BY THE SECRETARY, | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138104-A1 | Peptides | PTMS, VIP, CPB1 | AKR1B1 1526/4885BCAT2 37/4885KDM4E 2267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.